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Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm.

ABSTRACT: Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm.

PROVIDER: PRJNA1242889 | ENA |

REPOSITORIES: ENA

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Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm [ATAC-seq]

Project description:We discovered a role for the transcription factor OTX2 in formation of mouse definitive endoderm (DE). We used ATAC-seq to identify open chromatin regions in OTX2-depleted definitive endoderm cells and identify sites with changed accessibility during DE differentiation

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Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm [PS_CUTnRUN]

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Transcriptional remodeling by OTX2 directs specification and patterning of mammalian definitive endoderm.

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