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Expression data from ex vivo and cultured adipose-derived mesenchymal stromal cells (AdMSC, also known as ASC)

ABSTRACT: Expression data from ex vivo and cultured adipose-derived mesenchymal stromal cells (AdMSC, also known as ASC)

PROVIDER: PRJNA597007 | ENA |

REPOSITORIES: ENA

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Expression data from ex vivo and cultured adipose-derived mesenchymal stromal cells (AdMSC, also known as ASC)

Project description:The effect of standard tissue culture on AdMSC is not well defined, therefore we sought to analyse global changes in microRNA expression when a defined ex vivo population of AdMSC was subjected to standard tissue culture conditions.

2019-12-21 | GSE142429 | GEO

Adipose-derived stromal/stem cells (ASC)

Project description:Adipose-derived stromal/stem cells (ASC) capable of multipotential differentiation can be isolated with high yield from human subcutaneous lipoaspirates. This study reports our recent experience isolating and immunophenotypically characterizing ASCs from >60 human subjects

2010-10-01 | GSE18391 | GEO

Gene expression profiles of human retinal microvascular pericytes (HRMVPC) and human lipoaspirate derived mesenchymal stromal cells (adipose stromal cells, ASC)

Project description:Comparative gene expression profiles of human retinal pericytes (HRMPC) and lipoaspirate derived mesenchymal stromal cells (adipose stromal cells, ASC) cultivated either in normal (1g/l) or high (4.5g/l) glucose medium to identify similarities and discrepancies and elucidate high glucose effects considering cell-based therapies in diabetic retinopathy. A hallmark of diabetic retinopathy is pericyte- dropout increased vascular permeability and progressive vascular occlusion. ASC and HRMVPC were cultured in NG or HG for 7 days. Then cells were trypsinized, washed and RNA isolated using Qiagen RNeasy mini Kit (Qiagen, Hilden, Germany). RNA quality was tested by capillary electrophoresis on an Agilent 2100 Bioanalyzer (Agilent) and high quality (RNA integrity values ≥ 9) was confirmed.

2020-05-26 | GSE144605 | GEO

Expression data from ex vivo and cultured adipose-derived mesenchymal stromal cells (AdMSC)

Project description:Expression data from ex vivo and cultured adipose-derived mesenchymal stromal cells (AdMSC)

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Functional comparison between healthy and multiple myeloma adipose stromal cells

Project description:Multiple myeloma (MM) is a not curable B-cell neoplasia characterised by the accumulation of tumor plasma cells within the bone marrow. As a consequence, 80% of patients develop bone osteolytic lesions that remain even after complete remission. We and others had demonstrated that bone marrow derived Mesenchymal Stromal Cells (MSC) are abnormal in MM and thus could not be used for an autologous treatment to repare bone damages. Adipose Stromal Cells (ASC) represent an interesting alternative to MSC for cellular therapy. Thus, in this paper we asked if they could be a good candidate in repairing MM bone lesions. For the first time, we present a transcriptomic, phenotypic and functional comparison between ASC from MM patients and healthy donors (HD) relying on their autologous MSC counterpart. In contrast to MM MSC, MM ASC do not exhibit major abnormalities. However, the changes observed in MM ASC and the supportive property of ASC on MM cells question their putative and safety uses at autologous or allogenic level.

2019-06-27 | GSE133346 | GEO

Expression data from ex vivo and cultured adipose-derived mesenchymal stromal cells (AdMSC)

Project description:The effect of standard tissue culture on AdMSC is not well defined, therefore we sought to analyse global gene changes when a defined ex vivo population of AdMSC was subjected to standard tissue culture conditions.

2019-08-30 | GSE136633 | GEO

Project description:Drosophila melanogaster ex, expanded, is differentially expressed in 15 experiment(s);

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Project description:Drosophila melanogaster ex, expanded, is expressed in 3 baseline experiment(s);

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Gene expression profiles of human retinal microvascular pericytes (HRMVPC) and human lipoaspirate derived mesenchymal stromal cells (adipose stromal cells, ASC)

Project description:Gene expression profiles of human retinal microvascular pericytes (HRMVPC) and human lipoaspirate derived mesenchymal stromal cells (adipose stromal cells, ASC)

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Project description:In this study, the proteome and metabolic properties of primary subcutaneous (s) and visceral (v) adipose tissue-derived stromal stem cells (ASC) from old and young rabbits were analysed by a mass spectrometry-based label-free quantification approach and combined with metabolic mitochondrial respiration measurements (Seahorse Mito Cell Stress Test, Agilent).

2025-01-19 | PXD057467 | Pride

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