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In mammalian species, the first days after birth are an important period for survival and the rates of mortality before weaning are high. In pigs, the perinatal deaths average 20% of the litter, with important economic and societal consequences. Among the factors influencing piglet survival at birth...
2020-07-07 | MTBLS1541 | MetaboLights
Background: Congenital cytomegalovirus (cCMV) is a common intrauterine infection, leading to neurodevelopmental disabilities. Early prognostic assessment of the severity of cCMV has remained an ongoing challenge. We aimed to identify amniotic fluid biomarkers of the severity of cCMV-related fetal br...
ORGANISM(S): Homo sapiens (Human) Cytomegalovirus sp. 
2022-05-25 | PXD029105 | Pride
The goal of the experiment was to uncover novel TTTS biomarkers using microarray gene expression analysis of cell free fetal RNA from the amniotic fluid of TTTS-affected and non-affected pregnant women.
ORGANISM(S): Homo sapiens 
To understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from TTTS cases and controls revealed differential expression of 801 genes, which were significantly enri...
ORGANISM(S): Homo sapiens 
To understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from TTTS cases and controls revealed differential expression of 801 genes, which were significantly enri...
ORGANISM(S): Homo sapiens 
Congenital diaphragmatic hernia (CDH) results from incomplete diaphragm development and can be associated with pulmonary hypoplasia, pulmonary hypertension, and heart failure. Currently, few biomarkers are available. Since amniotic fluid comprises proteins of both fetal and maternal origin, its anal...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041165 | Pride
In this study, we carried out a comprehensive comparative proteomic and transcriptomic analysis of exosomes in amniotic fluid supernatant and cells in amniotic fluid precipitation of severe fetal hydronephrosis patients to identify candidate biomarkers with diagnostic potential. As the investigation...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD033988 | Pride
Congenital diaphragmatic hernia (CDH) is a severe birth defect frequently associated with pulmonary hypoplasia, pulmonary hypertension, and heart failure. Since amniotic fluid comprises proteins of both fetal and maternal origin, its analysis could provide insights on mechanisms underlying CDH and p...
ORGANISM(S): Homo sapiens (Human) 
2023-11-03 | PXD041859 | Pride
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
Transcriptome of amniotic fluid in vervet monkey
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