brown norway rat model

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Transcriptomics (1008)
Unknown (92)
Metabolomics (80)
Proteomics (63)
Genomics (58)
Other (1)

Organisms

Rattus norvegicus (758)
Mus musculus (142)
Homo sapiens (114)
Rattus rattus (12)
Strongyloides ratti (3)
Gallus gallus (3)
Drosophila melanogaster (3)
Danio rerio (3)
Arabidopsis thaliana (3)
Bacteroides fragilis 638R (2)
Mus musculus domesticus (2)
Trypanosoma brucei (2)
Staphylococcus aureus (2)
Bos taurus (2)
Plasmodium falciparum (2)
Saccharomyces cerevisiae (2)
Spalax carmeli (1)
Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 (1)
Thermococcus onnurineus NA1 (1)
Nannospalax galili (1)
Ascaris suum (1)
Streptococcus mutans UA159 (1)
Callithrix jacchus (1)
Taeniopygia guttata (1)
Toxoplasma gondii (1)
Enterococcus faecium (1)
mixed sample (1)
Streptococcus pneumoniae (1)
Ovis aries (1)
Escherichia coli (1)

Organisms

Rattus norvegicus (18)
Homo sapiens (1)

Repository

biostudies-arrayexpress (1034)
MetaboLights (80)
ENA (25)
MassIVE (20)
iProX (16)
jPOST (11)
geo (8)
pride (7)
PAXDB (6)
EGA (3)
PanoramaPublic (3)

Tissue

Visual cortex (2)
Retina (2)
Blood vessel (1)
Seed (1)
Liver (1)

Disease

Normal (10)
Glaucoma (2)
Pheocromocytoma cell line (1)
Pheochromocytoma (1)
Uninjured (1)
Cocaine addiction (1)
Model of metabolic syndrome (1)
Alzheimer's disease (1)
Ischaemia reperfusion injury (1)
Hypertension (1)
Pneumococcal meningitis (1)
Subarachnoid hemorrhage NOS (1)
Insulin resistance (1)
Photoreceptor degeneration (1)
Angiogenic chondrosarcoma (1)
Sham surgery (1)
Colon carcinoma (1)
Tumor (1)
Fibrosis (1)
Glioblastoma (1)
Cardiovascular system disease (1)

Technology Type

Mass spectrometry (42)
Mass spectrometry assay (32)
Mass Spectrometry (7)
NMR spectroscopy (6)
Shotgun proteomics (4)
Bottom-up proteomics (3)

Instrument Platform

Illumina NovaSeq 6000 (23)
Illumina HiSeq 2500 (16)
NextSeq 500 (13)
Illumina HiSeq 4000 (8)
Illumina HiSeq 2000 (6)
Agilent High resolution C scanner (4)
Illumina HiSeq 1500 (4)
Qubit 4.0 Fluorometer/ Agilen 5300 Fragment Analyzer (2)
Illumina NovaSeq X (2)
NextSeq 550 (2)
FastPrep-24 5G bead beater, Qubit Fluorometer (1)
12 well TC-treated plate, LETs buffer, dry ice (1)
PromethION (1)
Computer and Applied Biosystems 7500 Real Time PCR Systems thermal cycler (1)
Illumina TruSeq (1)
Agilent 2100 Bioanalyzer, Applied Biosystems 7900HT Sequence Detection System, Illumina TruSeq Small RNA Sample Preparation Kit (1)
RNeasy mini Kit, Ribo-Zero Human/Mouse/Rat kit (1)
(Make:PerkinElmer,Model:ScanArray 4000XL) (1)
Agilent Bioanalyzer 2100 (1)
Agilent Microarray Scanner (1)
Agilent G2565BA scanner (1)
Agilent Hybridization Oven (1)
Agilent G2565BA Microarray Scanner System (Agilent Technologies) (1)
Tecan HS4800 hybridization station (Tecan) (1)
Agilent Hybridization Oven. (1)
Agilent G2565BA scanner. (1)
Affymetrix GeneChip Scanner 3000 7G (1)
Agilent 2100 Bioanalyzer (1)
Affymetrix GeneChip Scanner 3000 (1)
HP GeneArray [Affymetrix/HP] (1)

Publication Date

2014 (116)
2010 (116)
2015 (111)
2013 (109)
2012 (96)
2008 (88)
2016 (81)
2011 (72)
2009 (71)
2007 (56)
2026 (42)
2021 (34)
2022 (31)
2025 (26)
2020 (22)
2024 (20)
2023 (20)
2017 (16)
2019 (12)
2018 (11)
2006 (11)
2005 (6)
2004 (3)
2003 (1)

UNIPROT ID/AC

F7HF82_MACMU (5)
F7AMR7_MACMU (5)
H9G1C0_MACMU (5)
9544.ENSMMUP00000025930 (5)
F6RPZ9_MACMU (5)
9544.ENSMMUP00000028270 (5)
A0A1D5QWS0_MACMU (5)
9544.ENSMMUP00000034943 (5)
TPIS_MACMU (5)
9544.ENSMMUP00000018001 (5)
G7N6Q4_MACMU (5)
I0FUX3_MACMU (5)
F7ACB4_MACMU (5)
9544.ENSMMUP00000007378 (5)
9544.ENSMMUP00000041218 (5)
F7HT55_MACMU (5)
F7CJE4_MACMU (5)
H9Z5Y2_MACMU (5)
9544.ENSMMUP00000000740 (5)
A0A5F8AV28_MACMU (5)
A0A1D5Q5B3_MACMU (5)
9544.ENSMMUP00000018047 (5)
H9FPI0_MACMU (5)
F7HSC9_MACMU (5)
A0A5F8AUN0_MACMU (5)
9544.ENSMMUP00000028220 (5)
F6SPY0_MACMU (5)
A0A1D5Q3Q0_MACMU (5)
9544.ENSMMUP00000038491 (5)
F7EDG2_MACMU (5)

CHEBI ID

CHEBI:16919 (17)
CHEBI:17596 (16)
CHEBI:17154 (15)
CHEBI:17368 (15)
CHEBI:30769 (15)
CHEBI:16704 (15)
CHEBI:15891 (15)
CHEBI:15428 (14)
CHEBI:17568 (14)
CHEBI:16737 (14)
CHEBI:18012 (13)
CHEBI:6650 (13)
CHEBI:15741 (13)
CHEBI:30915 (12)
CHEBI:15354 (12)
CHEBI:16015 (12)
CHEBI:17203 (12)
CHEBI:7916 (12)
CHEBI:15676 (11)
CHEBI:18237 (11)
CHEBI:28842 (11)
CHEBI:16027 (11)
CHEBI:17268 (11)
CHEBI:17895 (11)
CHEBI:15756 (11)
CHEBI:18089 (11)
CHEBI:20067 (11)
CHEBI:17295 (11)
CHEBI:15971 (11)
CHEBI:25094 (10)

Metabolite Name

Uracil (23)
Hypoxanthine (21)
Inosine (21)
Creatinine (20)
Pantothenic acid (20)
Taurine (20)
Uridine (20)
Xanthosine (18)
Creatine (18)
Cholic acid (17)
Citrulline (16)
Taurocholic acid (15)
Indole (15)
Kynurenic acid (15)
Choline (15)
L-Isoleucine (15)
Cytosine (15)
Oleamide (15)
Uric acid (15)
Serotonin (14)
Allantoin (14)
Hippuric acid (14)
Riboflavin (14)
L-Phenylalanine (14)
L-Threonine (14)
L-Proline (14)
Xanthine (14)
Urocanic acid (13)
Niacinamide (13)
Deoxycholic acid (13)

First Public Date

2014 (11)
2024 (3)
2021 (3)
2022 (2)
2023 (1)
2020 (1)
2019 (1)
2018 (1)
2013 (1)
2010 (1)

Study type

Transcription profiling by array (810)
RNA-seq of coding RNA (93)
ChIP-seq (18)
Unknown experiment type (15)
RNA-seq of non coding RNA (10)
Comparative genomic hybridization by array (9)
Methylation profiling by high throughput sequencing (9)
Animal - High-throughput sequencing (8)
Methylation profiling by array (8)
Animal - One-color microarray (7)
RNA-seq of coding RNA from single cells (6)
ChIP-chip by tiling array (4)
Other (4)
RNA-seq of total RNA (4)
ChIP-chip by array (3)
Transcription profiling by RT-PCR (3)
MicroRNA profiling by high throughput sequencing (3)
Transcription profiling by SAGE (2)
Genotyping by array (2)
MicroRNA profiling by array (2)
Transcription profiling by MPSS (1)
RIP-chip by array (1)
Animal - Single-cell sequencing (1)
Cell line - One-color microarray (1)
Translation profiling (1)
High-throughput sequencing (1)
ATAC-seq (1)
Ribo-seq (1)
ScATAC-seq (1)
DNA-seq (1)

Release Date

2014 (123)
2010 (119)
2015 (107)
2013 (107)
2012 (100)
2008 (89)
2016 (81)
2009 (74)
2011 (73)
2007 (55)
2022 (29)
2021 (26)
2019 (19)
2020 (18)
2017 (18)
2023 (15)
2018 (14)
2024 (13)
2025 (11)
2006 (11)
2026 (10)
2005 (8)
2004 (3)
2003 (2)
1999 (1)

Lab affiliation

Institute of Agriculture and Natural Resources, Food Science and Technology, University of Nebraska-Lincoln, NE, United States (1)
Professor and Robert A. Welch Chair in Biochemistry Department of Pharmacology and Neuroscience University of North Texas, Health Science Center (1)
Professor and Robert A. Welch Chair in Biochemistry Department of Pharmacology and Neuroscience University of North Texas Health Science Center at FortWorth (1)
Professor and Robert A. Welch Chair in Biochemistry Department of Pharmacology and Neuroscience UNT Helth at Fort Worth (1)
Professor and Robert A. Welch Chair in Biochemistry Department of Pharmacology and Neuroscience UNT Health at Fort Worth (1)
Institute of Physiology of the Czech Academy of Sciences, Laboratory of Genetics of Model Diseases (1)
Proteomics Core Facility, University of Gothenburg (1)

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Tissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights

Serum Metabolomics in the Rat Model of Recurrent Pelvic Pain

This study aimed to investigate systemic metabolic alterations underlying pain-depression comorbidity in the Recurrent Pelvic Pain (RPP) rat model using untargeted serum metabolomics (UPLC-Q-Orbitrap-MS). Comparative analysis revealed distinct metabolic profiles, identifying 234 differential meta...

2026-02-11 | MTBLS13869 | MetaboLights

Untargeted metabolomics profiling of esophageal tissues from a rat model of reflux esophagitis treated with Shunwei Jiangni Decoction

This dataset contains raw untargeted metabolomics data generated from esophageal tissue samples of rats in a reflux esophagitis (RE) model. The study aimed to characterize metabolic alterations associated with RE pathogenesis and to evaluate the regulatory effects of Shunwei Jiangni Decoction (SW...

2026-04-10 | MTBLS14112 | MetaboLights

Transcription profiling of rat liver samples from animals treated with D-penicillamine and controls

Idiosyncratic drug reactions (IDRs) cause significant morbidity and mortality. In an animal model of IDRs, 50-80% of Brown Norway rats exposed to D-penicillamine develop an autoimmune syndrome after several weeks of treatment. The symptoms of the IDR are similar to that observed in humans who take D...

ORGANISM(S): Rattus norvegicus

2007-10-10 | E-GEOD-2825 | biostudies-arrayexpress

Rat serum transcriptomic data

study investigated the anti-fatigue effect of the Panax ginseng–Astragali Radix (GGJ) herb pair, the core functional unit of Baoyuan Decoction, using a rat fatigue model induced by forced swimming. Serum samples were collected for untargeted metabolomics analysis by LC-MS/MS to profile differenti...

2026-06-30 | MTBLS14902 | MetaboLights

Therapeutic Effect of Buyang Huanwu Decoction on the Gut Microbiota and Hippocampal Metabolism in a Rat Model of Cerebral Ischemia

Buyang Huanwu decoction (BHD) is a well-known Chinese herbal prescription. It has been widely used in the clinical treatment of cerebral ischemia (CI) in China. However, the mechanism underlying the treatment of CI with BHD remains to be elucidated. In this study, we combined microbiomic and meta...

2022-06-02 | MTBLS4366 | MetaboLights

Therapeutic effects of traditional Chinese medicine compound Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota

Hua-Feng-Dan is a traditional Chinese medicine compound used to treat ischemic stroke, but little is known about its therapeutic mechanism. This study explored whether and how the mechanism involves readjustment of gut microbiota. Rats were subjected to middle cerebral artery occlusion as a model...

2025-01-06 | MTBLS10818 | MetaboLights

Transcription profiling of rat model of aging - progressive aortic vasculopathy

This study utilized a standard rat model of aging and global gene expression analyses to attempt to identify the most appropriate time points to study vascular aging and to identify molecules associated with the development of pathology. Recent studies have established that age is the major risk fac...

ORGANISM(S): Rattus norvegicus

2008-06-15 | E-GEOD-7281 | biostudies-arrayexpress

Gene Expression Profiling of the Retina after Transcorneal Electrical Stimulation in Wildtype Brown Norway Rats

Purpose: To investigate the effect of transcorneal electrical stimulation (TES) on the retina of wildtype Brown Norway (BN) rats by gene expression profiling. Methods: TES was applied to BN adult wildtype rat retina in vivo for 1h (1ms biphasic pulses at 20Hz; current: 200 M-BM-5A). RNA was isolated...

ORGANISM(S): Rattus norvegicus

2011-11-21 | E-GEOD-26174 | biostudies-arrayexpress

Untargeted metabolomics of offspring rats in MIA model

Maternal immune activation is a significant environmental factor for neurodevelopmental diseases. Although gut bacteria and their metabolites are linked to behavioral deficits in NDDs, the roles of gut fungi and secondary fungal metabolites remain unclear. Here, we induced MIA via a single intrap...

2026-01-20 | MTBLS12687 | MetaboLights

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