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ProteomicsA non-canonical SWI/SNF complex underlies synthetic lethality in cancers driven by BAF complex perturbation
Mammalian SWI/SNF chromatin remodeling complexes exist in three distinct, final-form assemblies: canonical BAF (cBAF), PBAF, and a newly characterized non-canonical complex, ncBAF. However, their complex-specific targeting on chromatin, functions and roles in disease remain largely unknown. Here, we...
ORGANISM(S): Homo sapiens (Human) 
2018-11-06 | PXD011103 | Pride
Brd7 Mswi/snf Chromatin remodeling Brd9 Baf Dpf2 
ProteomicsBRAHMA-containing chromatin remodelling complex prevailing in Arabidopsis vegetative organs is a homolog of mammalian non-canonical SWI/SNF complexes and requires BRD subunits for assembly and stability
The SWI/SNF family of chromatin remodeling complexes is evolutionarily conserved and present in yeast, animals and plants. While the biological functions of plant SWI/SNF complexes have been studied in detail, their composition is still elusive. To clarify this picture we used protein extracts from ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-04-03 | PXD030928 | Pride
Arabidopsis Brm Brahma Brd Swi/snf 
GenomicsA non-canonical SWI/SNF complex underlies synthetic lethality in cancers driven by BAF complex perturbation [ChIP-seq]
A non-canonical SWI/SNF complex underlies synthetic lethality in cancers driven by BAF complex perturbation [ChIP-seq]
PRJNA449855 | ENA
GenomicsRegulation of transcriptional interference by the Swi/Snf complex [nanopore]
Regulation of transcriptional interference by the Swi/Snf complex [nanopore]
PRJNA956883 | ENA
GenomicsA non-canonical SWI/SNF complex underlies synthetic lethality in cancers driven by BAF complex perturbation [RNA-seq]
A non-canonical SWI/SNF complex underlies synthetic lethality in cancers driven by BAF complex perturbation [RNA-seq]
PRJNA449854 | ENA
GenomicsRegulation of transcriptional interference by the Swi/Snf complex [RNA-seq]
Regulation of transcriptional interference by the Swi/Snf complex [RNA-seq]
PRJNA956077 | ENA
GenomicsRegulation of transcriptional interference by the Swi/Snf complex [Mnase-seq]
Regulation of transcriptional interference by the Swi/Snf complex [Mnase-seq]
PRJNA956071 | ENA
UnknownA non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.
Not available
S-EPMC6698386 | biostudies-literature
GenomicsRegulation of transcriptional interference by the Swi/Snf complex [ChIP-seq]
Regulation of transcriptional interference by the Swi/Snf complex [ChIP-seq]
PRJNA956070 | ENA
UnknownSWI/SNF Complex-Deficient Undifferentiated Carcinoma of the Pancreas: Clinicopathologic and Genomic Analysis.
Not available
S-EPMC11585460 | biostudies-literature
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