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MetabolomicsNitrate Reductase NarGHJI Modulates Vancomycin Susceptibility by Coordinating Cell Wall Remodeling and Agmatine Metabolism in Staphylococcus aureus
Staphylococcus aureus is a ubiquitous pathogen responsible for a wide range of severe infections. Our previous work established that the nitrate reductase NarGHJI modulates bacterial pathogenicity through regulation of the agr system, yet its role in antibiotic resistance remains poorly understood. ...
2026-07-07 | MTBLS14968 | MetaboLights
ProteomicsWheat grain cell wall enriched proteome
The aim of this project is to highlight cell wall proteome of wheat developing at two key stage of its development (150 GDD : middle of endosperm cellularisation and 250 GDD : start of grain filling with storage compounds). It's the first study of wheat grain cell wall proteome in which endosperm w...
ORGANISM(S): Triticum aestivum (Wheat) 
2020-05-27 | PXD016258 | Pride
Grain Cell wall Cereal Wheat 
ProteomicsCell wall proteome of wheat developing grain
The aim of this project is to highlight cell wall proteome of wheat developing at a key stage of its development (=250 GDD, start of grain filling with storage compounds). It's the first study in which endosperm were separated of outer layers in order to gain more information about the mechanisms o...
ORGANISM(S): Triticum aestivum (Wheat) 
2018-10-16 | PXD010367 | Pride
Wheat grain Cell wall 
ProteomicsFlax cell wall proteome - A cell wall proteome and targeted cell wall analyses provide novel information on hemicellulose metabolism in flax
Proteomic analyses of four different flax organs/tissues (inner-stem, outer-stem, leaves and roots) enriched in proteins from 3 different sub-compartments (soluble-, membrane-, and cell wall-proteins) was combined with publically available data on flax seed and whole-stem proteins to generate a flax...
ORGANISM(S): linum usitatissimum 
2017-07-19 | PXD005003 | Pride
Lc-msms Cell wall Flax 
ProteomicsSecretome of rat smooth muscle cells with stretch
The extracellular matrix (ECM) is fundamental to cellular and tissue structural integrity and provides mechanical cues to initiate diverse biological functions1. The quality and quantity of ECM determines tissue stiffness and controls gene expression, cell fate, and cell cycle progression in various...
ORGANISM(S): Rattus Rattus (black Rat) 
2020-03-18 | PXD013915 | JPOST Repository
MetabolomicsIDH1 Reprograms Nucleotide Metabolism by Inducing Chromatin Remodeling and DHODH Transcription to Drive Chemoresistance in Nasopharyngeal Carcinoma

Metabolic reprogramming under therapeutic stress may represent a targetable vulnerability for cancer treatment. Elucidation of the metabolic alterations linked to chemotherapy in nasopharyngeal carcinoma (NPC) could uncover potential therapeutic strategies. Using proteomics and transcriptomic pro...

2026-01-14 | MTBLS11531 | MetaboLights
TranscriptomicsTranscription profiling of models of cardiac remodelling: myocardial infarction or transverse aortic constriction in left ventricle free wall and septum
We employed the Affymetrix GeneChip technology to evaluate the patterns of expression in two different in vivo models of cardiac remodeling and in two different regions (left ventricle free wall and septum) of the heart. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI)...
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-415 | biostudies-arrayexpress
ProteomicsTime-Resolved Analysis of the Cell Wall Proteome in Saccharomyces cerevisiae S288c During Batch Fermentation
In this study, we aimed to characterize the temporal remodeling of the yeast cell wall proteome during the progression of a batch culture in a bioreactor using a rich medium. The model organism used was Saccharomyces cerevisiae strain S288c, cultivated in rich medium. Cell samples were collected at ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-09-07 | PXD071725 | Pride
Proteomics Yeast Bioreactor Cell wall Batch culture Kinetics Lc-ms/ms 
OtherCarbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans
PXD ID: PXD000008. Original data file: CW1113_q1 GluLac walls rep 2.mgf. Data published as part of Proteomics 2012 12:3164-79 . From Proteomexchange: {{i}}Cell wall and secretome preparation. C. albicans RM1000 cells grown to mid-exponential phase were harvested by centrifugation. The resulting sup...
ORGANISM(S): Candida_albicans 
GPM11210010990 | GPMDB
Resource Reanalysis 
GenomicsCandida albicans adapts to toxic levels of the quorum sensing molecule farnesol through cell wall remodeling
Candida albicans adapts to toxic levels of the quorum sensing molecule farnesol through cell wall remodeling
PRJNA792608 | ENA
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