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MetabolomicsEffects of hypoxic preconditioning on neuroblastoma tumour oxygenation and metabolic signature in a chick embryo model
Hypoxia episodes and areas in tumours have been associated with metastatic dissemination and poor prognosis. Given the link between tumour tissue oxygen levels and cellular metabolic activity, we hypothesised that the metabolic profile between metastatic and non-metastatic tumours would reveal poten...
2018-08-13 | MTBLS541 | MetaboLights
TranscriptomicsAnatomical and molecular dissection of the prestreak chick embryo
This paper shows detailed information of prestreak stage chick embryos at the morphological level by using scanning electron microscopy, and at the molecular level by RNAseq and expression analysis.
ORGANISM(S): Gallus gallus 
2020-02-12 | E-MTAB-7941 | biostudies-arrayexpress
TranscriptomicsTranscription profiling during differentiation of the neural tube in HH stage 10 chick embryos
The spinal cord is generated progressively as cells leave the caudal region of the elongating body axis such that the temporal steps of neural differentiation become spatially separated along the head to tail axis. At key stages, it is therefore possible to isolate near-adjacent cell populations fro...
ORGANISM(S): Gallus gallus 
2014-08-01 | E-MTAB-2734 | biostudies-arrayexpress
TranscriptomicsBMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors
The transition from progenitor to differentiated cells is critical for successful organogenesis; subtle alterations in this process can lead to developmental disorders. The anterior heart field (AHF) encompasses a niche in which cardiac progenitors maintain their multipotent and undifferentiated nat...
ORGANISM(S): Gallus gallus 
2010-08-01 | E-GEOD-19698 | biostudies-arrayexpress
TranscriptomicsAnalysis of retinoid targets in chick embryo wing buds
Chick wing buds at Hamburger and Hamilton stage 20 were treated with DMSO, all trans retinoic acid or synthetic retinoid EC23 via ion-exchange beads implanted into the wing buds. The anterior third of treated wing buds of surviving embryos were removed 24 hours after treatment by microdissection and...
ORGANISM(S): Gallus gallus 
2020-12-31 | E-MTAB-2545 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of chick embryonic tissues: gastrulation, neural tube/notochord and limb development.
Microarray analysis of chick embryo tissues: Hamburger Hamilton (HH) stage 3+/4 and HH6 Hensen’s node, HH 3+/4 posterior primitive streak, notochord with ventral neural tube at HH10-11, dorsal neural tube at HH10-11 and anterior and posterior thirds of the wing bud at stages HH20-21 and HH24.
ORGANISM(S): Gallus gallus 
2016-08-23 | E-MTAB-4048 | biostudies-arrayexpress
TranscriptomicsChick Otic Placode Induction Arrays
The inner ear develops from a patch of thickened cranial ectoderm adjacent to the hindbrain called the otic placode. Studies in a number of vertebrate species suggest that the initial steps in induction of the otic placode are regulated by members of the Fibroblast Growth Factor (FGF) family, and th...
ORGANISM(S): Gallus gallus 
2012-12-12 | E-GEOD-42845 | biostudies-arrayexpress
TranscriptomicsA 3D molecular atlas of the chick embryonic heart
We performed a detailed analysis of gene expression in the 2-day (HH12) embryonic chick heart. RNA-seq of 13 microdissected heart regions reveals regionalised expression of about 15,000 genes (Dataset 1). Of these, 131 genes that are differentially expressed (FPKM ≥20, fold change ≥1.1-4.0) within a...
ORGANISM(S): Gallus gallus 
2019-10-02 | E-MTAB-7663 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of chicken anterior and posterior wing bud thirds from stage HH24 normal and talpid3 mutant embryos
Relative levels of RNA transcripts were compared between anterior and posterior wing bud thirds from stage HH24 normal and talpid3 mutant chicken embryos using chicken Affymetrix chips. Data collected with Affymetrix scanner was normalized using the Plier algorithm within the expression console pack...
ORGANISM(S): Gallus gallus 
2010-08-12 | E-MTAB-309 | biostudies-arrayexpress
GenomicsChick Cranial Small RNA-seq
Chick Cranial Small RNA-seq
PRJNA720305 | ENA
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