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MetabolomicsClinical features and Multiomics Profiles Indicate Coagulation and Platelet Dysfunction as Key Pathological Pathways in COVID-19 Viral Sepsis
Background: The role of viral infections as a mediator of systemic immune dysfunction leading to sepsis has received limited attention compared to the bacterial pathogens. The COVID-19 pandemic and the increased cases of sepsis in the absence of known bacterial pathogens have highlighted the clinica...
2025-12-05 | MTBLS9664 | MetaboLights
TranscriptomicsVirus-misplaced host protein activates innate immunity
Discrimination between self vs. non-self and adequate response to infection and tissue damage are fundamental functions of the immune system. The rapid and global spread of known and emerging viruses is a testament that the timely detection of viral pathogens that reproduce within host cells, presen...
ORGANISM(S): Mus musculus 
2012-10-03 | E-GEOD-36078 | biostudies-arrayexpress
MetabolomicsA Divergent Selection on Breast Meat Ultimate pH, a Key Factor for Chicken Meat Quality, is Associated With Different Circulating Lipid Profiles

BACKGROUND: Chicken meat has become a major source of protein for human consumption. However, the quality of the meat is not yet under control, especially since pH values that are too low or too high are often observed. In an attempt to get a better understanding of the genetic a...

2022-06-01 | MTBLS2970 | MetaboLights
GenomicsGene expression analysis after selective expression of coagulation factor FVII
Gene expression analysis after selective expression of coagulation factor FVII
PRJNA491486 | ENA
TranscriptomicsRecombinant and plasma-derived Factor VIII products induce distinct splenic cytokine microenvironments in hemophilia A
To investigate the gene expression in dendritic cells after treating hemiphilic mice with HBSS, plasma derived or recombinant factor VIII Gene expression in dendritic cells were measured 24 hours post treatment Hemophilic mice with treated with either (HBSS, rFVIII or pdFVIII) 24 hours post treatmen...
ORGANISM(S): Mus musculus 
2010-05-19 | E-GEOD-15809 | biostudies-arrayexpress
GenomicsMacrophage-expressed coagulation factor 7 promotes adverse cardiac remodeling
Macrophage-expressed coagulation factor 7 promotes adverse cardiac remodeling
PRJNA1128140 | ENA
ModelsBravo2012 - Modelling blood coagulation factor Va inactivation by APC
Mathematical model of blood coagulation factor Va and Va fragment inactivation by APC, reactions with Xa and prothrombinase-prothrombin complex formation.
2024-09-02 | BIOMD0000000739 | BioModels
ModelsBaugh1998 - Regulation of coagulation factor Xa by TFPI
Basic mathematical model of the formation of coagulation factor Xa involving TF:VIIa and its inhibition by TFPI.
2018-07-18 | MODEL1807180001 | BioModels
UnknownImportant roles of the human leukocyte antigen class I and II molecules and their associated genes in the autoimmune coagulation factor XIII deficiency via whole-exome sequencing analysis.
Not available
S-EPMC8432773 | biostudies-literature
TranscriptomicsTranscription profiling of human pulmonary artery endothelial cell culture treated with Chapel Hill Ultrafine particle
Epidemiology studies have linked exposure to pollutant particles to increased cardiovascular mortality and morbidity, however, the mechanism remains unknown. In this study, we hypothesized that the ultrafine fraction of ambient pollutant particles would cause endothelial cells dysfunction. We profi...
ORGANISM(S): Homo sapiens 
2009-05-02 | E-GEOD-4567 | biostudies-arrayexpress
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