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Crassulacean acid metabolism (CAM) is a water-use efficient adaptation of photosynthesis that has evolved independently many times in diverse lineages of flowering plants. We hypothesize that convergent evolution of protein sequence and temporal gene expression underpins the independent emergences o...
2018-01-09 | MTBLS519 | MetaboLights

225 years ago, Alexander von Humboldt observed the first crassulacean acid metabolism (CAM) tree, Clusia rosea (Clusiaceae). Since then, the photosynthetic and ecophysiological plasticity of Clusia

species have captivated the minds of plant scientists worldwide. CAM is a physiological adapt...

2026-03-23 | MTBLS14075 | MetaboLights
Resource limitation is a major driver of ecological and evolutionary dynamics of organisms. Short-term responses to resource limitation include plastic changes in molecular phenotypes including protein expression. Yet little is known about the evolution of the molecular phenotype under longer-term r...
ORGANISM(S): Chlamydomonas reinhardtii 
2018-11-08 | PXD010847 | Pride
Adaptive evolution is generally assumed to progress through the accumulation of beneficial mutations. However, deleterious mutations may also have an important role by promoting adaptive genetic changes that are otherwise inaccessible. Here we study the capacity of the bakerM-bM-^@M-^Ys yeast genome...
ORGANISM(S): Saccharomyces cerevisiae BY4741 
Convergent Epigenetic Evolution Drives Relapse in Acute Myeloid Leukemia
Much of posttranscriptional mRNA regulation occurs through cis-acting sequences in mRNA 3´ untranslated regions (UTRs), which interact with specific proteins and ribonucleoprotein complexes that modulate translation, mRNA stability and subcellular localization. Studies in Caenorhabditis elegans hav...
ORGANISM(S): Caenorhabditis elegans 
Hox genes are required during the morphogenesis of both vertebrate digits and external genitals.We investigated whether transcription in such distinct contexts involves a shared enhancer-containing landscape. We show that the same regulatory topology is used, yet with some tissue-specific enhancer-p...
ORGANISM(S): Mus musculus 
Convergent phenotypic evolution of the visual system via different molecular routes: How Neotropical cichlid fishes adapt to novel light environments
How novel gene functions evolve is a fundamental question in biology. Mucin proteins, a functionally but not evolutionarily defined group of proteins, allow to study convergent evolution of gene function. By analyzing the genomic variation of mucins across a wide range of mammalian genomes, we propo...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Mus musculus (Mouse) Mustela putorius furo (European domestic ferret) (Mustela furo) Canis familiaris (Dog) (Canis lupus familiaris) Rattus norvegicus (Rat) Sus scrofa domesticus (domestic pig) 
2022-10-15 | PXD033197 | Pride
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