Sort   by:  
 Page size 
MetabolomicsAnalysis of DJ-1 Knockout Mouse Brains
Not available
ORGANISM(S): Mus musculus 
ST000260 | MetabolomicsWorkbench
TranscriptomicssiRNA profiling of human H157 non-small cell lung carcinoma cells with and without DJ-1 expression knocked-down
DJ-1 expression protects H157 cells from cell death, using siRNA oligomers we knocked down DJ-1 and evaulated gene expression using Affymetrix U133A GeneChip arrays. Experiment Overall Design: H157 cells were transfected every 24 hours with siRNA oligomers for 3 consecutive days, lysed 96 hours afte...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-5519 | biostudies-arrayexpress
GenomicsFusobacterium necrophorum DJ-1
Fusobacterium necrophorum DJ-1 Genome sequencing and assembly
PRJNA232678 | ENA
ProteomicsBN-PAGE analysis of DJ-1 KO dopaminergic neurons
We subjected digitonin-soluble lysates of DJ-1 KO and isogenic control neurons to non-denaturing blue-native PAGE (BN-PAGE) to visualize and separate multi-subunit protein complexes associated with DJ-1.
ORGANISM(S): Homo sapiens (Human) 
2025-12-23 | PXD069553 | Pride
Dopaminergic neurons Dj-1 Bn-page 
TranscriptomicsParkinson's disease-associated DJ-1 is required for the expression of GDNF receptor Ret in human neuroblastoma cells
DJ-1 is an atypical peroxiredoxin-like peroxidase that may act as a redox-dependent chaperone and a regulator of transcription. To explore DJ-1-mediated transcriptional control in Parkinsonâ??s disease (PD), we generated human neuroblastoma cells with inducible knock-down of DJ-1 expression. We then...
ORGANISM(S): Homo sapiens 
2010-04-28 | E-GEOD-17204 | biostudies-arrayexpress
ProteomicsPTM and HDX-MS analysis of DJ-1
1. PTM analysis results of DJ-1 1D-gel bands under non-reducing and reducing condition 2. HDX-MS analysis of DJ-1
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD020690 | Pride
Oxidation Dj-1 Hdx-ms 
ProteomicsLFQ of 3-phosphoglyceroyl lysine peptides from WT and DJ-1 KO HeLa cells
WT or DJ-1 KO HeLa cells (n=3) were lysed in 500 μL of 6 M guanidine-HCl, 100 mM HEPES-NaOH, pH 7.5, 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication, followed by centrifugation at 20,000 x g for 15 min at 4 ºC. The supernatants were recovered and proteins (1 mg each) ...
ORGANISM(S): Homo Sapiens (human) 
2025-05-07 | PXD063699 | JPOST Repository
ProteomicsLFQ of carboxymethyl/carboxyethyl lysine peptides from WT and DJ-1 KO HeLa cells
WT or DJ-1 KO HeLa cells (n=3) were lysed in 500 μL of 6 M guanidine-HCl, 100 mM HEPES-NaOH, pH 7.5, 10 mM TCEP, and 40 mM CAA. The lysates were dissolved by heating and sonication, followed by centrifugation at 20,000 x g for 15 min at 4 ºC. The supernatants were recovered and proteins (1 mg each) ...
ORGANISM(S): Homo Sapiens (human) 
2025-05-07 | PXD063705 | JPOST Repository
ProteomicsiTRAQ Analysis of DJ-1 Knockout Rodent Brains
Mutations in the DJ-1 (Park7) gene cause autosomal recessive Parkinson's disease in humans, but the function of the DJ-1 protein is poorly characterized. In an effort to understand more about the biology of DJ-1, we performed iTRAQ analyses on subcellular fractions enriched from DJ-1 knockout rat an...
ORGANISM(S): Mus musculus (Mouse) Rattus norvegicus (Rat) 
2017-10-04 | PXD005215 | Pride
Cytosol Itraq Dj-1 Mitochondria Hexokinase Parkinson's Neurodegeneration Subcellular fractionation Aging 
ProteomicsOxSWATH applied to in-vitro the characterization of redox state of recombinant DJ-1 proteins
Most of the redox proteomics strategies are focused on the identification and relative quantification of cysteine oxidation changes without considering the variation in the total levels of the proteins. However, the regulation of protein synthesis and protein degradation are also associated with man...
ORGANISM(S): Homo sapiens (Human) 
2019-02-16 | PXD006803 | Pride
Redoxomics  cysteine oxidation  swath-ms  differential alkylation  recombinant dj-1 
Sort   by:  
 Page size