Sort   by:  
 Page size 
MetabolomicsExposure to environmental hazard pesticide rotenone triggers redox driven system-wide lipidome alterations and metabolic trade-offs linked to Parkinson’s disease

With the global rise in aging populations, the increasing incidence of neurodegenerative diseases underscores concerns about brain health, with pesticides like rotenone, emerging as key environmental hazardous. The precise mechanism by which chronic environmental concentration of rotenone exposur...

2025-01-28 | MTBLS11699 | MetaboLights
ProteomicsSerum Peptidome: Diagnostic Window into Pathogenic Processes following Occupational Exposure to Carbon Nanomaterials
Growing industrial use of carbon nanotubes and nanofibers (CNT/F) warrants consideration of human health outcomes. CNT/F produces pulmonary, cardiovascular, and other toxic effects in animals, with significant augmentation of bioactive circulating peptides, the serum peptidome. While epidemiology am...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-26 | MSV000087305 | MassIVE
ProteomicsCharacterization of complement C3 as a marker of alpha-amanitin toxicity by comparative secretome profiling
In the human body, proteins secreted into peripheral blood vessels are known as the secretome, and they represent the physiological or pathological status of cells. The unique response of cells to toxin exposure can be confirmed via secretome analysis, which can be used to discover toxic mechanisms ...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-23 | PXD038016 | Pride
Alpha-amanitin  toxic mushroom  secretomes  exposure marker  complement component 3 
ProteomicsCharacterization of hepatocytes secretomes after alpha-amanitin exposure by quantitative proteomics
In the human body, proteins secreted into peripheral blood vessels are known as the secretome, and they serve as a representation of the physiological or pathological status of cells. The unique response of cells to toxin exposure can be confirmed via secretome analysis, which can be applied to disc...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD036476 | Pride
Alpha-amanitin  toxic mushroom  secretomes  exposure marker  complement component 3 
ProteomicsCalretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat
The effect of prenatal and lactational exposure to 4 mixtures of endocrine-didsrupting compounds (Antiandrogen mix, AA; Estrogenic mix, E; Paracetamol, P, and Totalmix, TM) on the early postnatal ovary.
ORGANISM(S): Rattus norvegicus (Rat) 
2020-04-01 | PXD015470 | Pride
Proteomics Rat Prenatal edc exposure Ovary 
TranscriptomicsTranscription profiling of human lymphoblastoid cells following 3 Gy and 10 Gy of ionizing radiation exposure to identify transcriptional response of lymphoblastoid cells to ionizing radiation
Time series for gene expression changes following 3 Gy and 10 Gy of ionizing radiation exposure.
ORGANISM(S): Homo sapiens 
2007-09-21 | E-GEOD-701 | biostudies-arrayexpress
TranscriptomicsImmediate Transcriptional Changes in Response to High Dose Radiation Exposure
One of the most likely risks astronauts on long duration space missions face is exposure to ionizing radiation associated with highly energetic and charged heavy (HZE) particles. Since access to medical expertise on such a mission is limited at best, early diagnosis and mitigation of such exposure ...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-64375 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in zebrafish brain after acute exposure to domoic acid at symptomatic and asymptomatic doses
Domoic acid (DA) is a neuroexcitatory amino acid that is naturally produced by some marine diatom species of the genus Pseudo-nitzschia. Ingestion of DA-contaminated seafood by humans results in a severe neurotoxic disease known as amnesic shellfish poisoning (ASP). Clinical signs of ASP include s...
ORGANISM(S): Danio rerio 
2009-07-06 | E-GEOD-12140 | biostudies-arrayexpress
TranscriptomicsDanio rerio larvae exposed to SSRIs Fluoxetine and Sertraline
Pharmaceutical chemicals used in human medicine are released into surface waters via municipal effluents and pose a risk for aquatic organisms. Among these substances are selective serotonin reuptake inhibitors (SSRIs) which can affect aquatic organisms at sub ppb concentrations. To better underst...
ORGANISM(S): Danio rerio 
2012-09-06 | E-GEOD-31712 | biostudies-arrayexpress
ProteomicsDiscovery of Noninvasive Biomarkers for Radiation Exposure via LC-MS-based Hair Metabolomics
Ionizing radiation exposure from a potential nuclear energy plant leak or detonation of a nuclear weapon can cause massive casualties to both warfighters and civilians. Biomarkers in biological specimens like blood and tissue, such as RNA, proteins, and metabolites, have shown potential to determine...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-10-24 | MSV000096204 | MassIVE
Sort   by:  
 Page size