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TranscriptomicsTranscription profiling of rat A7r5 vascular smooth muscle cells over-expressing glucose transporter
Hypothesis: Overexpression of the GLUT1 facilitative glucose transporter, in A7r5 vascular smooth muscle cells, is sufficient and/or necessary to induce alterations in gene expression which influence apoptosis, growth, and proliferation. Experiment Overall Design: Scientific Approach: A7r5 rat emb...
ORGANISM(S): Rattus norvegicus 
2009-11-07 | E-GEOD-15713 | biostudies-arrayexpress
ProteomicsMutations in disordered regions cause disease by creating dileucine motifs - BioID
Many disease-causing missense mutations affect intrinsically disordered regions (IDRs) of proteins. Since these mutations do not affect protein structure, the molecular mechanism of their pathogenicity is enigmatic. Here, we employ a peptide-based proteomic screen to investigate the impact of mutati...
ORGANISM(S): Homo sapiens (Human) 
2018-09-13 | PXD010061 | Pride
Bioid Proximity labeling 
TranscriptomicsmiR-143-5p suppresses breast cancer progression by targeting the HIF-1α-related GLUT1 pathway
Breast cancer (BC) is a commonly identified life-threatening type of cancer and a major cause of death among women worldwide. Several microRNAs (miRs), including miR-143-5p, have been reported to be vital for regulating hallmarks of cancer; however, the effect of miR-143-5p on BC requires further ex...
ORGANISM(S): Homo sapiens 
2022-02-26 | E-MTAB-11160 | biostudies-arrayexpress
ProteomicsBrain proteomics in GLUT1-deltaGFAP mice
Neuroproteomic analysis of GLUT1-deltaGFAP mice using SWATH-mass spectrometry
ORGANISM(S): Mus Musculus (mouse) 
2023-07-19 | PXD035376 | JPOST Repository
GenomicsAPP-deficiency impairs GLUT1 through defective growth factor signaling.
APP-deficiency impairs GLUT1 through defective growth factor signaling.
PRJNA1514623 | ENA
GenomicsGene expression profiles in cardiac specific overexpression of Glut1 transgenic mice
Gene expression profiles in cardiac specific overexpression of Glut1 transgenic mice
PRJNA434478 | ENA
ProteomicsMutations in disordered regions cause disease by creating dileucine motifs - PRM dataset-
Mutations in intrinsically disordered regions (IDRs) of proteins are associated with a wide spectrum of diseases. Since IDRs lack a fixed three-dimensional structure, the molecular mechanism by which such mutations cause disease is often unknown. Here, we employ a peptide-based proteomic screen to i...
ORGANISM(S): Homo sapiens (Human) 
2018-09-13 | PXD010005 | Pride
Glut1 Disordered regions Prm Dileucin 
ProteomicsK29-linked ubiquitination of GLUT1 on SCV promotes glucose acquisition by intravacuolar Salmonella
comparative interactome analysis and ubiquitination between bacteria-associated GLUT1 (BS-GLUT1) and native GLUT1
ORGANISM(S): Homo Sapiens 
PXD064768 |
ProteomicsA Pilot Proteogenomic Study With Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma
We performed a pilot proteogenomic study to compare lung adenocarcinoma to lung squamous cell carcinoma using quantitative proteomics (6-plex TMT) combined with a customized Affymetrix GeneChip. Using MaxQuant software, we identified 51,001 unique peptides that mapped to 7,241 unique proteins and fr...
ORGANISM(S): Homo sapiens (Human) 
2015-11-06 | PXD002622 | Pride
Non-small cell lung cancer Lung adenocarcinoma Tmt Mct1 Nsclc Lung squamous cell carcinoma Glut1 Proteogenomics Slc16a1 Slc2a1 
GenomicsGLUT1 overexpression enhances CAR T cell metabolic fitness and anti-tumor efficacy
GLUT1 overexpression enhances CAR T cell metabolic fitness and anti-tumor efficacy
PRJNA1104654 | ENA
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