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MetabolomicsBiosynthesis of polyamine–polyphosphate granules for colitis alleviation

Natural polyamines, such as spermidine and spermine, exert strong anti-inflammatory effects, but their therapeutic benefits are limited by rapid absorption in the small intestine, resulting in low colonic availability. In this study, engineered Citrobacter freundii overexpressing ppk1 (CPP) coul...

2026-01-07 | MTBLS13621 | MetaboLights
TranscriptomicsCSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline
P granules in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency.  Sterility in the absence of P granules is often accompanied by the mis-expression of soma-specific proteins and the initiation of somatic differentiation in germ cells.  To investigate ...
ORGANISM(S): Caenorhabditis elegans 
2015-05-20 | E-GEOD-67954 | biostudies-arrayexpress
ProteomicsProteomic Analysis of fly brain cytoplasmic RNP granules containing the lncRNA mimi
In neurons, mRNAs and associated RNA-binding proteins assemble into ribonucleoprotein (RNP) granules essential to regulate mRNA trafficking, local translation, and turnover. Dysregulation of RNA-protein condensation can disturb synaptic plasticity. We report that the novel lncRNA mimi is a constitut...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-10-12 | PXD034453 | Pride
Rnp granules  fly brain  neurons  lncrna mimi Fne  rbp9 Drosophila  relative ibaq  quantitative proteomics 
TranscriptomicsTracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: a Link Between Stalled Polyribosomes and RNA Granules
Local translation at the synapse plays key roles in neuron development and activity-dependent synaptic plasticity. mRNAs are translocated from the neuronal soma to the distant synapses as compacted ribonucleoparticles referred to as RNA granules. These contain many RNA-binding proteins, including th...
ORGANISM(S): Mus musculus 
2016-06-30 | E-GEOD-83835 | biostudies-arrayexpress
GenomicsAnammox granules
Anammox granules Raw sequence reads
PRJNA1456749 | ENA
GenomicsAD Granules
Study of Anaerobic Digester granules communities.
PRJEB40014 | ENA
TranscriptomicsRNA-seq of Rattus novergicus brain after stroke with Yangyin Tongnao granules for the treatment of the cerebral ischemia-reperfusion injury
In this study, the aim was to elucidate the mechanism of ischemic stroke in rats using a novel integrated transcriptomic. Transcriptomic data were obtained by Illumina-based RNA-seq technology. Then, transcriptomics was applied to dig out the reversed differentially expressed targets against IS indu...
ORGANISM(S): Rattus norvegicus 
2023-08-23 | E-MTAB-12143 | biostudies-arrayexpress
ProteomicsProteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion
Proteome of lysate granules using G3BP and ASPL, and changes in the G3BP interactome caused by ASPL depletion
ORGANISM(S): Homo sapiens (Human) 
2025-08-16 | PXD059889 | Pride
Ribonucleoprotein granule Aspscr1 Ubxd9 Tug Protein homeostasis Viscoelasticity Aspl Stress granule Rheology Vcp/p97 G3bp Ulk Multisystem proteinopathy 
GenomicsSingle Methanogenic Granules
Single Granules as highly-replicated whole-ecosystems
PRJEB29753 | ENA
ProteomicsThe Proteome and Transcriptome of Stress Granules and P-Bodies during Human T Lymphocytes Activation
Stress granules (SGs) and processing bodies (PBs) are membraneless cytoplasmic assemblies regulating mRNAs under environmental stress such as viral infections, neurological disorders, or cancer. Upon antigen stimulation, T lymphocytes mediate their immune functions under regulatory mechanisms involv...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD031639 | Pride
Human t lymphocytes Ribonucleoprotein granules Proteome 
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