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TranscriptomicsHiC data of the human oesophageal adenocarcinoma (EAC) cell lines OE19
This dataset consists of in situ HiC-seq data from a human oesophageal adenocarcinoma cell line (OE19). In total, the dataset includes 2 biological replicated samples. The Hi-C sample and library preparations were generated using Arima-HiC Kit (A510008, ARIMA Genomics) and Arima Library Prep module ...
ORGANISM(S): Homo sapiens 
2023-02-20 | E-MTAB-12664 | biostudies-arrayexpress
TranscriptomicsGWAS region focused capture-HiC of primary melanocytes from five human donors
Capture-HiC was conducted to map chromatin interactions at all melanoma GWAS identified risk-associated regions across five individual primary human melanocyte cultures. Capture-HiC baits were designed by Arima Genomics (San Diego, CA, 2x tiling, least stringent masking, XTHSBoosting) to obtain an A...
ORGANISM(S): Homo sapiens 
2025-04-24 | E-MTAB-15079 | biostudies-arrayexpress
TranscriptomicsMedulloblastoma tumors derived from Ptch+/-HIC+/- transgenic mouse allografted in nude mice
Nude mice were allografted with medulloblastoma tumors derived from Ptch+/-HIC+/- transgenic mouse and treated with vehicle or NVP-LDE225. RNA was prepared from tumours from vehicle or NVP-LDE225 treated nude mice allografted with medulloblastoma tumors derived from Ptch+/-HIC+/- transgenic mouse an...
ORGANISM(S): Mus musculus 
2010-09-29 | E-GEOD-22005 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling of Hic-5 knockdown in PshTert-AR human myofibroblasts
Identifying the effect of the co-regulator Hic-5 (TGFB1I1) on global androgen receptor transcriptional activity in PShTert-AR prostate fibroblast cells with view to further elucidating the broader biological role of Hic-5 on fibroblast spceific androgen signaling. Knockdown of Hic5 for 48 hours in ...
ORGANISM(S): Homo sapiens 
2013-08-26 | E-GEOD-47203 | biostudies-arrayexpress
ProteomicsCharacterisation of a Hic-5-proximal nuclear interactome
In addition to central functions in cell adhesion signalling, integrin-associated proteins have wider roles at sites distal to adhesion receptors. In experimentally defined adhesomes, we noticed that there is clear enrichment of proteins that localise to the nucleus, and conversely, we now report th...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-01 | PXD025868 | Pride
Hic-5 Adhesion Nucleus Human 
TranscriptomicsHiC-sequencing in human monocyte differentiation (3D-MO)
This dataset consists of in situ HiC-seq data from human monocytes, monocyte-derived dendritic cells as well as monocyte-derived cells that were subjected to siRNA treatment targeting CTCF or RAD21. In total, the data set includes 42 samples.
ORGANISM(S): Homo sapiens 
2022-06-24 | E-MTAB-10848 | biostudies-arrayexpress
GenomicsZhang GenomePaint NALM16 HiC - samples
HiC files for GenomePaint paper titled "Exploration of coding and non-coding variants in cancer using GenomePaint."
EGAD00001006678 | EGA
ProteomicsProteomics exploiting modular baits with different subcellular locations reveal hydrogen peroxide-inducible clone 5 protein (HIC-5) and a glucocorticoid receptor variant as novel testin partners
The LIM domain and tumour suppressor protein Testin (Tes) is downregulated in a variety of human tumours and tumour cell lines. Depending on its conformation, Tes localises to stress fibres and focal adhesions where it forms protein complexes with other members of the actin c...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD005058 | Pride
Imixpro Ip Proteomics Hic-5 Testin Gr Lc-ms/ms 
TranscriptomicsSelective enhancement and repression of glucocorticoid receptor signaling by coregulator Hic-5
The glucocorticoid receptor (GR) recruits many coregulators via the well characterized AF2 interaction surface in the GR ligand binding domain, but LIM domain coregulator Hic-5 binds to the relatively uncharacterized tau2 activation domain in the hinge region of GR. Requirement of Hic-5 for glucocor...
ORGANISM(S): Homo sapiens 
2014-03-21 | E-GEOD-46448 | biostudies-arrayexpress
GenomicsHiC training
BGE HiC training data
PRJEB96778 | ENA
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