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TranscriptomicsTranscription profiling of mouse C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression
Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this s...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8312 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skeletal muscle of integrin alpha7 overexpressing animals vs controlls
Analysis of integrin alpha7 transgenic mice skeletal muscle transcription profiles comparing to wild type controls. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dyst...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8313 | biostudies-arrayexpress
ProteomicsTargeted mass spectrum on activation-state-dependent Integrin alpha 5
Integrin alpha 5 is a key transmembrane protein that mediates cell-ECM adhesion and ECM assembly. Its activation and signaling involve both cytoplasmic and extracellular proteins. Using zebrafish somitogenesis as the physiological setting, we sought to identify activation-state-dependent Integrin al...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-10-13 | PXD058550 | Pride
Integrin activation Zebrafish somite Integrin alpha 5 Actin adaptor Integrin actin linker Integrin 
TranscriptomicsTranscription profiling of mouse epidermal cells sorted into three populations based on alpha 6 integrin, CD34 or Sca-1 surface marker expression
Epidermal keratinocytes were isolated from adult murine skin and FACS sorted into three populations based on their surface maker expression of alpha 6 integrin, CD34 and Sca-1.
- Alpha 6 positive cells constitute the entire population of basal or proliferative keratinocytes from the interfolli...
ORGANISM(S): Mus musculus 
2009-11-16 | E-MEXP-928 | biostudies-arrayexpress
UnknownStructural specializations of α(4)β(7), an integrin that mediates rolling adhesion.
Not available
S-EPMC3255974 | biostudies-literature
ProteomicsProteomic analysis of integrin-associated adhesion complexes isolated from cells treated with DMSO or FAK inhibitor
Human foreskin fibroblast cells were spread on fibronectin (FN) for 1 h and treated with DMSO or FAK inhibitor (3 uM, AZ13256675 (termed AZ675 for short)) for 1 h. Integrin-associated adhesion complexes isolated from these cells were analysed by mass spectrometry to determine changes in adhesion com...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-23 | MSV000080089 | MassIVE
TranscriptomicsFunctional blockade of α5β1 integrin induces scattering and genomic landscape remodeling of hepatic progenitor cells
Cells treated with a specific antibody against α5β1 integrin exhibited cell spreading and scattering, over-expression of liver stem/progenitor cell markers and activation of the ERK1/2 and p38 MAPKs signaling cascades, in a similar manner to the process triggered by HGF/SF1 stimulation. Gene express...
ORGANISM(S): Mus musculus 
2010-08-26 | E-GEOD-23853 | biostudies-arrayexpress
UnknownDeletion of integrin-linked kinase from skeletal muscles of mice resembles muscular dystrophy due to alpha 7 beta 1-integrin deficiency.
Not available
S-EPMC2111119 | biostudies-literature
UnknownEnhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.
Not available
S-EPMC2199213 | biostudies-literature
UnknownIncreasing alpha 7 beta 1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression.
Not available
S-EPMC2593740 | biostudies-literature
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