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ProteomicsGlobal Interferon-stimulated Genes Interactome Network
Interferon-stimulated genes (ISGs) form the backbone of innate immune system and are pivotal for limiting intra- and intercellular viral replication and spread. We conducted a mass spectrometry–based survey to understand the fundamental organization of the innate immune system and to explore molecul...
ORGANISM(S): Homo sapiens (Human) 
2019-03-01 | PXD012274 | Pride
Isg interactome Ifn Ap-lc-ms/ms 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-03-11 | PXD045812 | Pride
Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD045783 | Pride
Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-04-30 | PXD045916 | Pride
Viral replication Live-cell imaging Sars-cov-2 Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsThe ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes
The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Ut...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD045929 | Pride
Viral replication Live-cell imaging Sars-cov-2 Rtcb Innate immune system Interferon-stimulated genes (isgs) Arrayed knock-out screen Proteomics 
ProteomicsFluAV vRNP interactome - A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
Interferon-stimulated genes (ISGs) form the backbone of innate immune system and are pivotal for limiting intra- and intercellular viral replication and spread. We conducted a mass spectrometry–based survey to understand the fundamental organization of the innate immune system and to explore molecul...
ORGANISM(S): Homo sapiens (Human) 
2019-03-01 | PXD012275 | Pride
Influenza Rnps Fluav Ap-lc-ms/ms 
UnknownCoordinated regulation and widespread cellular expression of interferon-stimulated genes (ISG) ISG-49, ISG-54, and ISG-56 in the central nervous system after infection with distinct viruses.
Not available
S-EPMC1797448 | biostudies-literature
TranscriptomicsDynamic expression profiling of type I and type III interferon-stimulated hepatocytes.
This dataset details the time-dependent response of human Huh7 hepatoma cells to type I and type III IFN. Despite activating similar signaling cascades, the type I and type III interferons (IFNs) differ in their ability to antagonize viral replication. However, it is not clear whether these cytokine...
ORGANISM(S): Homo sapiens 
2013-08-22 | E-GEOD-48400 | biostudies-arrayexpress
UnknownAssessing the Differential Abundance of Maternal Circulating MicroRNAs or Interferon-Stimulated Genes with Early Pregnancy.
Not available
S-EPMC10454372 | biostudies-literature
UnknownInterferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20.
Not available
S-EPMC6002717 | biostudies-literature
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