intrinsically disordered domains

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Archaic chaos: intrinsically disordered proteins in Archaea.

Not available

S-EPMC2880407 | biostudies-literature

BRCA1/BARD1 intrinsically disordered regions facilitate chromatin recruitment and ubiquitylation

BRCA1/BARD1 is a tumor suppressor E3 ubiquitin (Ub) ligase with roles in DNA damage repair and in transcriptional regulation. BRCA1/BARD1 RING domains interact with nucleosomes to facilitate mono-ubiquitylation of distinct residues on the C-terminal tail of histone H2A. These enzymatic domains const...

ORGANISM(S): Homo sapiens (Human)

2023-06-21 | PXD035345 | Pride

Kinesin tail domains are intrinsically disordered.

Not available

S-EPMC3437001 | biostudies-literature

A bimodal distribution of two distinct categories of intrinsically disordered structures with separate functions in FG nucleoporins.

Not available

S-EPMC2953916 | biostudies-literature

Intrinsically Disordered Regions in Chromodomain Helicase DNA-binding (CHD) Proteins Shape Distinct Protein Interaction Networks

Metazoans employ chromodomain helicase DNA-binding (CHD) enzymes to reposition nucleosomal DNA for transcription and replication. The CHD family consists of nine distinct members (CHD1-9) that possess highly conserved chromo and ATPase domains. These domains are flanked by poorly characterised N- an...

ORGANISM(S): Homo sapiens (Human)

2025-05-26 | PXD055009 | Pride

Dna helicase Chromatin remodelers Transcription Intrinsically disordered regions Aggregation prone regions Protein-protein interactions

Intrinsically disordered proteins: modes of binding with emphasis on disordered domains.

Not available

S-EPMC8492171 | biostudies-literature

Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing.

Not available

S-EPMC6175956 | biostudies-literature

How disordered is my protein and what is its disorder for? A guide through the "dark side" of the protein universe.

Not available

S-EPMC5314888 | biostudies-literature

αα-Hub domains and intrinsically disordered proteins: A decisive combo.

Not available

S-EPMC7948954 | biostudies-literature

Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity

In development, pioneer transcription factors access silent chromatin to reveal lineage-specific gene programs. The structured DNA-binding domains of pioneer factors have been well characterized, but whether and how low-complexity intrinsically disordered regions (IDRs) affect chromatin and control ...

ORGANISM(S): Mus musculus (Mouse)

2024-06-16 | PXD043586 | Pride

Tcf-1 T-cells L1 Transcription factor Idrs

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