mesenchymal stem/stromal cells

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Organisms

Homo sapiens (262)
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Repository

biostudies-arrayexpress (848)
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Tissue

Cell culture (15)
Stem cell (14)
Mesenchymal cell (11)
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Mesenchymal stem cell of the bone marrow (5)
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Primary cell (2)
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Disease

Disease free (5)
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AIDS-KS, HIV+, nodular (late) stage (1)
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Bone disease (1)
Brain cancer (1)
Breast cancer (1)
Cardiovascular system disease (1)
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Glioblastoma (1)
Liver cirrhosis (1)
Myxoid liposarcoma (1)
Osteoarthritis (1)
Osteoporosis (1)

Technology Type

Mass Spectrometry (56)
Shotgun proteomics (39)
Mass spectrometry (12)
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Data-dependent acquisition (4)
SWATH MS (4)
Data-independent acquisition (3)
Mass spectrometry assay (2)
Gel-based experiment (2)
Affinity purification coupled with mass spectrometry proteomics (1)
All-ion fragmentation (1)
DiaPASEF (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (21)
Q Exactive (15)
Illumina HiSeq 2500 (14)
Illumina HiSeq 4000 (14)
NextSeq 500 (13)
LTQ Orbitrap Velos (6)
Illumina HiSeq 2000 (5)
Illumina Genome Analyzer II (3)
DNBSEQ-T7 (3)
Feature Extraction Version: 7.0,10.5 (2)
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Ion Torrent S5 XL (2)
Illumina HiSeq 1500 (2)
TruSeq Stranded Total RNA kit (Illumina) (1)
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Computer (1)
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Not applicable (1)
AB SOLiD 4 System (1)
BAS-1800 [FUJIFILM] (1)
Illumina Genome Analyzer IIx (1)
Not provided (1)
NA (1)
10x Genomics Chromium Controller (1)
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DNBSEQ-G400 (1)
NextSeq 550 (1)
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Publication Date

2013 (122)
2014 (111)
2015 (109)
2010 (96)
2012 (95)
2016 (83)
2025 (78)
2011 (72)
2022 (69)
2008 (57)
2024 (54)
2026 (52)
2023 (50)
2021 (46)
2020 (46)
2009 (41)
2018 (40)
2017 (38)
2019 (36)
2007 (16)
2005 (4)
2006 (3)
2004 (3)

CHEBI ID

CHEBI:16708 (5)
CHEBI:16335 (5)
CHEBI:17368 (5)
CHEBI:16704 (4)
CHEBI:18050 (4)
CHEBI:16856 (4)
CHEBI:17568 (4)
CHEBI:16264 (4)
CHEBI:16027 (4)
CHEBI:16680 (4)
CHEBI:17596 (4)
CHEBI:5445 (3)
CHEBI:17822 (3)
CHEBI:17202 (3)
CHEBI:16610 (3)
CHEBI:28044 (3)
CHEBI:32805 (3)
CHEBI:48153 (3)
CHEBI:17533 (3)
CHEBI:15891 (3)
CHEBI:28875 (3)
CHEBI:6650 (3)
CHEBI:16196 (3)
CHEBI:27468 (3)
CHEBI:16040 (3)
CHEBI:16695 (3)
CHEBI:7916 (3)
CHEBI:16908 (3)
CHEBI:16015 (3)
CHEBI:16467 (3)

Metabolite Name

Inosine (6)
Adenosine (5)
Uridine (5)
Hypoxanthine (5)
Glutathione (4)
Adenine (4)
Glycodeoxycholic acid (3)
Cyclohexylamine (3)
Hydroxyphenyllactic acid (3)
Indolelactic acid (3)
Serotonin (3)
Choline (3)
Taurine (3)
Xanthosine (3)
Urocanic acid (3)
Spermidine (3)
Cytosine (3)
Leu-Val (3)
L-Glutamine (3)
Xanthine (3)
Guanosine (3)
Thymidine (3)
Creatinine (3)
Creatine (3)
Glycerophosphocholine (3)
L-Leucine (3)
C12-AS (2)
Ethyl 3-indoleacetate (2)
Ser-Glu (2)
Inosine 5'-monophosphate (2)

First Public Date

2014 (70)
2025 (53)
2026 (50)
2024 (42)
2022 (42)
2023 (37)
2020 (35)
2021 (31)
2019 (30)
2017 (19)
2018 (16)
2015 (8)
2016 (6)
2013 (3)

Modification

4 (1)
4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (601)
RNA-seq of coding RNA (85)
ChIP-seq (30)
Methylation profiling by array (29)
Other (12)
Transcription profiling by RT-PCR (11)
RNA-seq of coding RNA from single cells (11)
Unknown experiment type (7)
Comparative genomic hybridization by array (7)
Cell line - High-throughput sequencing (6)
MicroRNA profiling by array (6)
RNA-seq of non coding RNA (6)
RNA-seq of total RNA (5)
Methylation profiling by high throughput sequencing (4)
ChIP-chip by array (3)
Transcription profiling by SAGE (2)
ChIP-chip by tiling array (2)
Human - High-throughput sequencing (2)
RNAi profiling by array (2)
ATAC-seq (2)
Baseline (1)
Differential (1)
Animal - Single-cell sequencing (1)
Cell line - One-color microarray (1)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
Genotyping by array (1)
Capture-C (1)
Bisulfite-seq (1)
DNA-seq (1)

Release Date

2021 (295)
2020 (274)
2022 (264)
2023 (236)
2019 (208)
2016 (198)
2024 (188)
2015 (188)
2014 (185)
2018 (170)
2017 (170)
2025 (164)
2013 (159)
2012 (128)
2010 (124)
2011 (92)
2008 (58)
2009 (51)
2026 (31)
2007 (15)
2005 (6)
2006 (4)
2004 (3)
2001 (1)

Lab affiliation

Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Lisbon, Portugal. (2)
1) Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal 2) Instituto de Engenharia Biomédica (INEB), Universidade do Porto, Porto, Portugal 3) Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, Porto, Portugal (1)
1. Ludwig Boltzmann Institute for Traumatology The research center in cooperation with AUVA, Donaueschingenstrasse 13, 1200 Vienna, Austria 2. Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, 1200 Vienna, Austria (1)
Aalborg University Laboratory for Medical Massspectrometry (1)
Aalborg University; Translational biomarkers (1)
Aging and Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA (1)
Baker Heart and Diabetes Institute (1)
Biozentrum, University of Basel, Klinglebergstrasse 50/70, CH-4056 Basel (1)
CNC - Center for Neuroscience and Cell Biology, University of Coimbra (1)
CNRS UMS3444-Protein Science Facility (1)
Canadian Blood Services, Centre for Innovation, Ottawa, Ontario, Canada; Biochemistry, Microbiology and Immunology department, University of Ottawa, Ottawa, Canada. (1)
Centre for Oncology, Radiopharmaceuticals and Research, Biologic and Radiopharmaceutical Drugs Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, K1A 0K9, Canada (1)
Department of Anatomy and Cell Biology, Martin Luther University Faculty of Medicine, Halle (Saale), Germany (1)
Department of Biochemistry and Molecular Biology, University of Southern Denmark (1)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (1)
Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands (1)
Department of Laboratory Medicine and Advanced Biotechnologies, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IRCCS - ISMETT) Via Ernesto Tricomi, 5 - 90127 Palermo (1)
Department of Molecular Biolgy, Princeton University, USA (1)
Department of Molecular Medicine (DMM), Biochemistry Unit, Center for Health Technologies (CHT), UdR INSTM University of Pavia, Pavia, Italy (1)
Department of Musculoskeletal and Ageing Science, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK (1)
Department of Oral and Maxillofacial Surgery, West China Hospital of Stomatology, Sichuan University, (1)
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida (1)
Department of Science and Environment, Roskilde University, Roskilde, Denmark (1)
Division of Experimental Medicine, McGill University, Montreal, QC, Canada. (1)
Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University (1)
Division of Molecular Hematology, Department of Laboratory Medicine, Lund Univsersity, Sweden (1)
EMBL Heidelberg (1)
Faculty of Pharmacy, University of Helsinki, Helsinki, Finland. (1)
Focus Area Leader Disc and Cartilage Biology, PhD, PD AO Research Institute Davos (ARI) (1)
Health Canada (1)

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Mesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights

Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights

Combined Mesenchymal Stem Cells and Metformin Therapy Modulates Key Macromolecular Pathways in Pulmonary Fibrosis: Evidence from Untargeted Metabolomics

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. Current treatment options remain limited, driving interest in novel therapeutic approaches. Mesenchymal stem cells (MSCs) possess immunomodulatory and regenerative properties, while metformin, traditionally ...

2025-08-25 | MTBLS12893 | MetaboLights

Proteome characterization of mesenchymal stem cells and exosomes

Proteome characterization of mesenchymal stem cells (MSC) and exosomes. MSCs were cultured in normoxic, hypoxic and in presence of FBS. Exosomes were prepared from normoxic and hypoxic conditions.

ORGANISM(S): Homo Sapiens (human)

2021-04-27 | PXD025584 | JPOST Repository

Mesenchymal stem cell integrin-associated complexes

The composition and stiffness of the extracellular matrix (ECM) environment that surrounds Multipotent mesenchymal stem cells (MSCs) stem cells dictates transcriptional programming, thereby affecting stem cell lineage decision-making. Cells sense force between themselves and their microenvironment ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079956 | MassIVE

Multi-omics approach to identify age-related changes in mesenchymal stem cells

Mesenchymal stem cells (MSC) are bone-marrow derived cells, capable of multipotent differentiation into connective tissues including bone, tendon and cartilage. They are an attractive source for autologous cell-based treatments for a range of clinical diseases and injuries. MSCs have been demonstra...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-22 | MSV000079981 | MassIVE

Proteomic analysis of human Wharton's jelly mesenchymal stem/stromal cells and human amniotic epithelial stem cells: a comparison of therapeutic potential

Background: Perinatal stem cells have prominent applications in cell therapy and regenerative medicine. Among them, human Wharton's jelly mesenchymal stem/stromal cells (hWJMSCs) and human amniotic epithelial stem cells (hAESCs) are widely used. However, little is known about the dif-ferences in the...

ORGANISM(S): Homo Sapiens

2023-08-02 | PXD044276 |

Comprehensive transcriptomic and proteomic characterization of human mesenchymal stem cells reveals source specific cellular markers

Mesenchymal stem cells (MSC) are multipotent cells with great potential in therapy, reflected by more than 500 MSC-based clinical trials registered with the NIH. MSC are derived from multiple tissues but require invasive harvesting and imply donor-to-donor variability. Embryonic stem cell-derived MS...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-03-31 | MSV000080827 | MassIVE

Direct contact with mesenchymal stromal cells impacts CD133+ hematopoietic stem cells during ex-vivo expansion

Direct contact with mesenchymal stromal impacts on migratory behavior and gene expression profile of CD133+ hematopoietic stem cells during ex-vivo expansion Objective: To investigate the impact of direct contact between mesenchymal stromal cells (MSCs) and CD133+ hematopoietic stem cells (HSCs) in ...

ORGANISM(S): Homo sapiens

2008-11-12 | E-GEOD-13566 | biostudies-arrayexpress

Proteomic analysis of human Wharton's jelly mesenchymal stem cells and human amniotic epithelial stem cells: a comparison of therapeutic potential

proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells

ORGANISM(S): Homo Sapiens

2024-06-05 | PXD052844 |

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