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TranscriptomicsAssessing concordance of drug-induced transcriptional response in rodent liver and cultured hepatocytes
The effect of drugs, disease and other perturbations on mRNA levels are studied using gene expression microarrays or RNA-seq, with the goal of understanding molecular effects arising from the perturbation. Previous comparisons of reproducibility across laboratories have been limited in scale and fo...
ORGANISM(S): Rattus norvegicus 
2015-11-12 | E-GEOD-74903 | biostudies-arrayexpress
UnknownIntegrated proteotranscriptomics of breast cancer reveals globally increased protein-mRNA concordance associated with subtypes and survival.
Not available
S-EPMC6276229 | biostudies-literature
GenomicsFeeding-Induced Discordance: Protein-mRNA Correlation Varies by Zone, Sex, and Fasting in Mouse Hepatocytes
Feeding-Induced Discordance: Protein-mRNA Correlation Varies by Zone, Sex, and Fasting in Mouse Hepatocytes
PRJNA1232797 | ENA
TranscriptomicsFeeding-Induced Discordance: Protein-mRNA Correlation Varies by Zone, Sex, and Fasting in Mouse Hepatocytes
The mammalian liver plays an essential role in maintaining metabolic homeostasis in response to fasting and feeding. Additionally, the liver exhibits sex dimorphism and zonation. To investigate how these factors interact, we performed RNA-seq and proteomics on periportal and pericentral hepatocytes ...
ORGANISM(S): Mus musculus 
2025-04-22 | GSE291303 | GEO
ProteomicsAnalysis of Human Breast Tumors by Integrated Proteotranscriptomics
We generated large-scale proteome data for 65 human breast tumors and 53 paired adjacent non-cancerous tissue and performed an integrated proteotranscriptomic characterization. To our best knowledge, the study is one of the largest quantitative proteomic study of human breast tissues, including the ...
ORGANISM(S): Homo sapiens (Human) 
2018-12-04 | PXD005692 | Pride
Breast cancer proteomics 
TranscriptomicsConcordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA
This SuperSeries is composed of the following subset Series: GSE18834: Human Argonaute Immunoaffinity Purification-associated RNA. GSE18835: mRNA abundance in HEK293T cells mock or miR-124 transfected. GSE18836: Translation Profiling +/- miR-124. GSE18837: Unamplified mRNA abundance in miR-124 and m...
ORGANISM(S): Homo sapiens 
2009-11-09 | E-GEOD-18889 | biostudies-arrayexpress
ProteomicsSimultaneous profiling of native-state proteomes and transcriptomes of brain cell types using proximity labeling
Deep molecular phenotyping of cells at transcriptomic and proteomic levels is an essential first step to understanding cellular contributions to development, aging, injury, and disease. Since proteome and transcriptome level abundances only modestly correlate with each other, complementary profiling...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-02-16 | PXD073954 | Pride
Proximity labeling  transcriptomics  proteomics  microglia  astrocytes  neurons  mrna-protein concordance 
ProteomicsSimultaneous profiling of native-state proteomes and transcriptomes of brain cell types using proximity labeling
Deep molecular phenotyping of cells at transcriptomic and proteomic levels is an essential first step to understanding cellular contributions to development, aging, injury, and disease. Since proteome and transcriptome level abundances only modestly correlate with each other, complementary profiling...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-16 | PXD059818 | Pride
Proximity labeling  transcriptomics  proteomics  microglia  astrocytes  neurons  mrna-protein concordance 
UnknownUncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor.
Not available
S-EPMC2367054 | biostudies-literature
UnknownWidespread discordance between mRNA expression, protein abundance and <i>de novo</i> lipogenesis activity in hepatocytes during the fed-starvation transition.
Not available
S-EPMC12080948 | biostudies-literature
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