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ProteomicsSeveral proteins are altered in serum of patients having colorectal cancer with variable levels of C-Reactive protein and different survival times
Colorectal cancer (CRC) is the third most common cancer worldwide. Increased levels of C-reactive protein (CRP), which occur during local and systemic inflammation, have been linked to poor prognosis in CRC patients. on the other hand there are no biomarkers associated with 5 year survival of CRC pa...
ORGANISM(S): Homo sapiens (Human) 
2018-03-26 | PXD008583 | Pride
Colerectal cancer  serum proteomics  multivariate data analysis  opls-da  insulin growth factor binding protein-2 
UnknownVolatile Fingerprinting and Regional Differentiation of Safflower (<i>Carthamus tinctorius</i> L.) Using GC-IMS Combined with OPLS-DA.
Not available
S-EPMC12523545 | biostudies-literature
MetabolomicsApplication of 1H-NMR Metabolomic Profiling for Reef-Building Corals
In light of global reef decline new methods to accurately, cheaply, and quickly evaluate coral metabolic states are needed to assess reef health. Metabolomic profiling can describe the response of individuals to disturbance (i.e., shifts in environmental conditions) across biological models and is a...
2014-11-20 | MTBLS116 | MetaboLights
MetabolomicsRole and Mechanism of SERPINA1/PLG/TGFB1-Induced Adipose Fibroblast Activation in Dorsal Cervical Adipose Accumulation
This untargeted metabolomics study investigates metabolic differences in human adipose tissue between Group A (n=7) and Group B (n=7). Samples were analyzed using LC-MS/MS in both positive and negative ion modes on a Thermo Q-Exactive HF-X mass spectrometer. A total of 2,305 metabolites were detecte...
2026-05-08 | MTBLS14456 | MetaboLights
MetabolomicsDiscovery and validation of potential serum biomarkers for heart failure by untargeted metabolomics

Detection of biomarkers was extremely important for the early diagnosis, prognosis and therapy optimization of diseases. The purpose of this study was to investigate the differences in serum metabolites between patients with heart failure (HF) and healthy controls (HC), and to diagnose HF qualita...

2025-07-18 | MTBLS9586 | MetaboLights
MetabolomicsComprehensive analysis of flavonoids metabolism and transcription in different parts of Houttuynia cordata

Houttuynia cordata is a medicinal plant with diverse pharmacological activities, but the relationship between its flavonoid components and gene expression across different plant parts remains poorly understood. This study aims to explore these relationships using metabolomics and transcriptomics ...

2026-01-24 | MTBLS12311 | MetaboLights
MetabolomicsUntargeted metabolomics analysis of gingival tissue in patients with severe periodontitis
Periodontitis, as a chronic inflammatory condition, its initiating factor is the plaque biofilm. The inflammation starts in the gingival tissue, if left untreated, may progress to severe periodontitis and cause bone and tooth loss. The purpose of this study was to determine the potential metabolic b...
2026-09-08 | MTBLS8357 | MetaboLights
MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
MetabolomicsCharacterization of Constituents with Potential Anti-Inflammatory Activity in Chinese Lonicera Species by UHPLC-HRMS Based Metabolite Profiling
This study centered on detecting potentially anti-inflammatory active constituents in ethanolic extracts of Chinese Lonicera species by taking an UHPLC-HRMS-based metabolite profiling approach. Extracts from eight different Lonicera species were subjected to both UHPLC-HRMS analysis and to pharmacol...
2022-11-17 | MTBLS3112 | MetaboLights
UnknownOPLS-Based Multiclass Classification and Data-Driven Interclass Relationship Discovery.
Not available
S-EPMC11863383 | biostudies-literature
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