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ProteomicsOxonium ion scanning mass spectrometry for large-scale plasma glycoproteomics
Protein glycosylation, a complex and heterogeneous post-translational modification that is frequently dysregulated in disease, has been difficult to analyse at scale. Here we report a data-independent acquisition technique for the large-scale mass-spectrometric quantification of glycopeptides in pla...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-05-29 | MSV000089567 | MassIVE
ProteomicsOxonium Ion-Guided Ion Mobility-Assisted Glycoproteomics on the timsTOF Pro
Spatial separation of ions in the gas-phase, providing information about their size as collisional cross-sections, can readily be achieved through ion mobility. The timsTOF Pro combines a trapped ion mobility device with a quadrupole, collision cell and a time-of-flight analyser to enable the analys...
ORGANISM(S): Homo sapiens (Human) 
2023-01-17 | PXD034845 | Pride
Tims N-glycopeptides Oxonium ions Plasma Neutrophils Ion mobility 
ProteomicsOxonium ion guided analysis of quantitative proteomics data reveals site-specific O-glycosylation of anterior gradient protein 2 (AGR2)
Developments in mass spectrometry (MS)-based analyses of glycoproteins have been important to study changes in glycosylation related to disease. Recently, the characteristic pattern of oxonium ions in glycopeptide fragmentation spectra had been used to assign different sets of glycopeptides. In part...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD025805 | Pride
Glycoproteomics  tmt labeling  oxonium ion  lc−ms/ms  o-glycosylation  colorectal cancer  agr2 
UnknownData-independent oxonium ion profiling of multi-glycosylated biotherapeutics.
Not available
S-EPMC6204843 | biostudies-literature
UnknownControl of stereogenic oxygen in a helically chiral oxonium ion.
Not available
S-EPMC10017494 | biostudies-literature
UnknownOxonium ion scanning mass spectrometry for large-scale plasma glycoproteomics.
Not available
S-EPMC10963274 | biostudies-literature
UnknownInvolvement of an Oxonium Ion Intermediate in Controlling the Diastereoselectivity of Nucleophilic Substitution Reactions of Septanoses.
Not available
S-EPMC9850862 | biostudies-literature
UnknownOxonium Ion Guided Analysis of Quantitative Proteomics Data Reveals Site-Specific O-Glycosylation of Anterior Gradient Protein 2 (AGR2).
Not available
S-EPMC8160981 | biostudies-literature
UnknownOxonium Ion-Guided Optimization of Ion Mobility-Assisted Glycoproteomics on the timsTOF Pro.
Not available
S-EPMC9853368 | biostudies-literature
UnknownOn Silylated Oxonium and Sulfonium Ions and Their Interaction with Weakly Coordinating Borate Anions.
Not available
S-EPMC7028070 | biostudies-literature
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