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ProteomicsAnalysis of the yeast peptidome and comparison with the human peptidome
Peptides function as signaling molecules in species as diverse as humans and yeast. Mass spectrometry-based peptidomics techniques provide a relatively unbiased method to assess the peptidome of biological samples. In the present study, we used a quantitative peptidomic technique to characterize the...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-06-02 | PXD004800 | Pride
Mass spectrometry Saccharomyces cerevisiae Proteasome Peptidome 
Proteomicscold exposure peptidome of male
cold exposure alters peptidome in hippocampus ,hypothalamus and pituitary connected with microbiota in gut
ORGANISM(S): Mus Musculus 
2022-10-17 | PXD037471 |
ProteomicsImpact of CD74 knockdown on the HLA peptidome of the H1 melanoma cell line
The influence of CD74 expression on the HLA peptidome of the H1 melanoma cell line was analyzed by label-free quantitation mass spectrometry of HLA ligand extracts obtained from CD74 siRNA & control siRNA treated cells.
ORGANISM(S): Homo sapiens (Human) 
2018-03-01 | PXD008937 | Pride
Hla peptidome Melanoma Cd74 
ProteomicsOptimising sample preparation of the plasma peptidome
We further expanded on previous optimizations to isolate the plasma peptidome and compared various methods to maximize identifications with speed and ease. Previous studies have reported loss of polypeptides binding to high abundant proteins during depletion strategies. We hypothesized that rapid c...
ORGANISM(S): Homo sapiens (Human) 
2017-10-09 | PXD007191 | Pride
Peptidomics Plasma Sample preparation 
ProteomicsMultiplexed temporal quantification of the human plasma peptidome
The plasma peptidome contains the entire complement of low molecular weight endogenous peptides derived from secretion, protease activity and post-translational modifications and is a rich source of biomarkers and novel bioactives. To examine the utility of peptidomics we have examined the effects o...
ORGANISM(S): Homo sapiens (Human) 
2017-11-21 | PXD004781 | Pride
Peptidomics Exercise Peptidome Plasma 
ProteomicsSerum Peptidome Profiles Immune Response of COVID-19 Vaccine Administration
The study shows the promise of MALDI-TOF MS-based serum peptidome analysis for the assessment of immune responses activated by COVID-19 vaccination, and discovered a panel of serum peptides biomarkers for COVID-19 vaccination and for NAbs generation. The method developed in this study can help not o...
ORGANISM(S): Homo Sapiens 
2022-08-19 | PXD036159 |
UnknownAnalysis of the Yeast Peptidome and Comparison with the Human Peptidome.
Not available
S-EPMC5042401 | biostudies-literature
ProteomicsThe effect of proteasome inhibition on the HLA peptidome
The Major histocompatibility complex (MHC) class I peptidome is thought to be generated mostly through proteasomal degradation of cellular proteins, a notion that is based on the alterations in presentation of selected peptides following proteasome inhibition. We evaluated the effects of proteasome ...
ORGANISM(S): Homo sapiens (Human) 
2018-11-27 | PXD000171 | Pride
Hla peptidome Proteasome inhibitors Dynamic silac 
ProteomicsNon-pregnant CVF peptidome - Discovery of Antimicrobial Peptides in Cervical-vaginal Fluid from Healthy Non-pregnant Women Via an Integrated Proteome and Peptidome Analysis
Cervical-vaginal fluid (CVF) covers the lower part of the female reproductive system and functions in the homeostasis and immunity of the surrounding tissues. The proteome of this proximal fluid has mainly been studied in pregnant women, whereas the CVF proteome of non-pregnant women has not been an...
ORGANISM(S): Homo sapiens (Human) 
2017-09-27 | PXD004450 | Pride
Cvf peptidome Lc-ms/ms 
ProteomicsIdentification of tumor antigens in the HLA peptidome of patient-derived xenograft tumors in mouse
Personalized cancer immunotherapy targeting patient-specific cancer/testis (CTA) antigens and neoantigens may benefit from large-scale tumor HLA peptidome (immunopeptidome) analysis, which aims to accurately identify antigens presented by tumor cells. While significant efforts have been invested in ...
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD016060 | Pride
Patient derived xenograft Tumor antigen Peptidome Hla 
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