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ProteomicsAnaerobic peroxisomes in Entamoeba histolytica metabolize myo-inositol
E. histolytica is believed to be devoid of peroxisomes, like most anaerobic protists. In this work, we provided the first evidence that peroxisomes are present in E. histolytica, although the set of proteins (peroxins) responsible for peroxisome biogenesis was reduced to only seven members (Pex1, Pe...
ORGANISM(S): Entamoeba histolytica 
2021-10-29 | PXD026653 | Pride
Inositol dehydrogenase Peroxisomes Entamoeba histolytica Pts1 Pex 
ProteomicsA PEROXO-Tag enables rapid isolation of peroxisomes from human cells
Peroxisomes are metabolic organelles that perform a diverse array of critical functions in human physiology. Traditional isolation methods for peroxisomes can take more than one hour to complete and can be laborious to implement. To address this, we have now extended our prior work on rapid organell...
ORGANISM(S): Homo sapiens (Human) 
2020-05-20 | PXD018880 | Pride
Human hek-293t Peroxisome Peroxo-ip 
ProteomicsProximity tagging identified mitofusins stimulating mitochondria and peroxisomes clustering
we applied a proximity tagging system PUP-IT to PEX ubiquitin ligase to identify their proximal proteins. Surprisingly, we identified many mitochondrial proteins in the proximity of peroxisomes. We further validated the interaction between PEX and mitofusins (MFNs).
ORGANISM(S): Homo Sapiens 
2022-03-19 | PXD032661 |
GenomicsPeroxisomes are dispensable for normal renal function.
Peroxisomes are dispensable for normal renal function.
PRJNA742694 | ENA
TranscriptomicsPeroxisomes are signaling patforms for antiviral innate immunity
Analysis of the transcriptional response of mouse embryonic fibroblasts to reovirus infection. The hypothesis tested was that both peroxisomal and mitochondrial MAVS is capable of inducing the expression of antiviral genes. mRNA isolated from MAVS-expressing cells after infection for various times ...
ORGANISM(S): Mus musculus 
2010-11-04 | E-GEOD-21215 | biostudies-arrayexpress
TranscriptomicsC10ORF10/DEPP, a transcriptional target of FOXO3 regulates ROS-sensitivity by destabilizing peroxisomes in human neuroblastoma
FOXO transcription factors control cellular formation of reactive oxygen species (ROS), which critically contribute to cell survival and cell death in neuroblastoma. Here, we report that C10orf10, also named M-bM-^@M-^\Decidual Protein induced by Progesterone (DEPP)M-bM-^@M-^], is a direct transcrip...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-53046 | biostudies-arrayexpress
GenomicsPeroxisomes in maintenance and neural differentiation of mESCs
Peroxisomes in maintenance and neural differentiation of mESCs
PRJNA1372731 | ENA
ProteomicsThe Hansenula polymorpha Mitochondrial Carrier Family protein Mir1 is dually localized at peroxisomes and mitochondria
Peroxisomes are ubiquitous cell organelles involved in various metabolic pathways. In order to properly function, several cofactors, substrates and products of peroxisomal enzymes need to pass the organellar membrane. So far only a few transporter proteins have been identified. We analysed peroxisom...
ORGANISM(S): Hansenula polymorpha vector pAM619 
2024-05-10 | PXD050324 | Pride
Mitochondrial carrier family Peroxisomes Mitochondria Transporter proteins Mir1 Dual localization 
GenomicsPeroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
Peroxisomes are critical for a unique metabolic demand and survival of alveolar macrophages
PRJNA1222440 | ENA
GenomicsIntegrative Omics reveals changes in the cellular landscape of yeast without peroxisomes
Integrative Omics reveals changes in the cellular landscape of yeast without peroxisomes
PRJNA1086399 | ENA
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