Sort   by:  
 Page size 
ProteomicsPlectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis – subcellular in vitro profiling
The most common primary malignancy of the liver, hepatocellular carcinoma (HCC), is a heterogeneous tumor entity with high metastatic potential and complex pathophysiology. Increasing evidence suggests that tissue mechanics plays a critical role in tumor onset and progression. Here we show that plec...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD060086 | Pride
Hepatocellular carcinoma  plectin  plecstatin-1 Target Metastasis 
ProteomicsPlectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis – in vivo profiling
The most common primary malignancy of the liver, hepatocellular carcinoma (HCC), is a heterogeneous tumor entity with high metastatic potential and complex pathophysiology. Increasing evidence suggests that tissue mechanics plays a critical role in tumor onset and progression. Here we show that plec...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-22 | PXD060054 | Pride
Hepatocellular carcinoma  plectin  plecstatin-1 Target Metastasis 
ProteomicsPlectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis – in vitro phosphoproteomics
The most common primary malignancy of the liver, hepatocellular carcinoma (HCC), is a heterogeneous tumor entity with high metastatic potential and complex pathophysiology. Increasing evidence suggests that tissue mechanics plays a critical role in tumor onset and progression. Here we show that plec...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD060083 | Pride
Hepatocellular carcinoma  plectin  plecstatin-1 Target Metastasis 
ProteomicsDevelopment of novel combination treatments in AML guided by proteomics profiling
Acute promyelocytic leukaemia (APL) can be cured by the co-administration of arsenic trioxide (ATO) and all-trans retinoic acid (ATRA). These small molecules relieve the differentiation blockade of the cancerous promyelocytes and trigger their maturation into functional neutrophils, which are physio...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD019619 | Pride
Aml Arsenic trioxide Cancer Apl Proteomics Differentiation Normalization Metal Plecstatin-1 Ruthenium 
UnknownA Proteomic Platform Enables to Test for AML Normalization In Vitro.
Not available
S-EPMC8844467 | biostudies-literature
UnknownPlectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.
Not available
S-EPMC11893104 | biostudies-literature
ProteomicsCancer Cell Extravasation Requires iPlectin Mediated Choreography of MT1-MMP at Invadopodia
Cancer cell extravasation is a key step of the metastatic cascade and an attractive therapeutic opportunity. Early steps in cancer cell extravasation require formation of tentacle-like protrusions called invadopodia that physically breach the endothelial barrier and degrade extracellular matrix (EC...
ORGANISM(S): Homo sapiens (Human) 
2025-03-28 | PXD039276 | Pride
Invadopodia Cancer Protein-protein interactions 
Sort   by:  
 Page size