proliferative retinopathy

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Multi-pathological condition. According with Working Group of the Sociedad Española de Medicina Interna (SEMI), a patients are defined as multi-pathological or polypathological when they have chronic diseases that belong to two or more of the eight next categories:-Category A: NYHA heart failure class II (slight limitation of physical activity, in which ordinary physical activity causes dyspnea, angina, fatigue or palpitations). Ischemic heart disease.- Category B: Vasculitis and systemic autoimmune diseases. Chronic kidney disease defined by elevated creatinine (>1.4 mg/dL in men or >1.3 mg/dL in women) or proteinuria (albumin/creatinine ratio >300 mg/g, microalbuminuria >3mg/dL in urine sample or albumin >300 mg/day in 24-hour urine, for 3 months).- Category C: Chronic respiratory disease classified as MCR grade 2 (unable to keep the pace of another person of the same age (1)
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Salivary biomarkers of diabetic retinopathy, part 1

To characterize human salivary proteome and determine changes in proteins expression in different stages of diabetic retinopathy.

ORGANISM(S): Homo sapiens (Human)

2016-04-26 | PXD003723 | Pride

gut microbiome of proliferative diabetic retinopathy

gut microbiome of proliferative diabetic retinopathy Metagenome

PRJNA753622 | ENA

Differences in Aqueous Humor Protein Profiles in Patients With Proliferative Diabetic Retinopathy Before and After Aflibercept Treatment

To investigate the changes in aqueous humor (AH) protein profiles before and after intravitreal aflibercept (IVA) treatment in patients with proliferative diabetic retinopathy (PDR) patients. 5 PDR patients provided 10 samples of AH before and after IVA treatment (pre-group vs post-group). Proteins ...

ORGANISM(S): Homo sapiens (Human)

2024-05-21 | PXD039210 | Pride

Proteomics Aflibercept Proliferative diabetic retinopathy Lc-ms/ms

Gene Expression Profile of Fibrovascular Membrane Associated with Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR) is a vision-threatening disorder characterized by the formation of cicatricial fibrovascular membranes leading to traction retinal detachment. Despite the recent advance in the treatment of PDR such as vitreoretinal surgery with use of anti-vascular endotheli...

ORGANISM(S): Homo sapiens

2014-08-16 | E-GEOD-60436 | biostudies-arrayexpress

Proteomics of Vitreous Humor Reveals Upstream Regulators of Proliferative Diabetic Retinopathy

To investigate the key regulators of the disease by comparing the abundance of vitreous proteins between the patients with proliferative diabetic retinopathy (PDR) and the controls with idiopathic epiretinal membrane (iERM).

ORGANISM(S): Homo Sapiens

2021-07-26 | PXD027556 |

Vitreous of proliferative diabetic retinopathy patients

PRJNA790455 | ENA

Serum Disease-specific IgG Fc Glycosylation as Potential Biomarkers for Nonproliferative and Proliferative Diabetic Retinopathy Using Mass Spectrometry

The patients were enrolled and categorized into three groups according to clinical diagnosis: non-diabetic retinopathy; nonproliferative diabetic retinopathy ; and proliferative diabetic retinopathy. Gel electrophoresis was performed to separate IgG from morning fasting blood samples and polyaniline...

ORGANISM(S): Homo sapiens (Human)

2025-06-16 | PXD057612 | Pride

Igg n-glycosylation Mass spectrometry Biomarkers. Diabetic retinopathy

Human PDR Vitreous Variability Study, TMT-MS

Control (n=27) and proliferative diabetic retinopathy (n=23) vitreous samples were treated as biologically distinct individuals or pooled together and aliquoted into technical replicates. Quantitative mass spectrometry with tandem mass tag labeling was used to identify proteins in individual or pool...

ORGANISM(S): Homo sapiens (Human)

2022-02-14 | PXD025986 | Pride

Proliferative diabetic retinopathy Vitreous Tmt-ms Human

Protein profile analysis of 12 human vitreous samples using labelfree method

To study the differences in protein profiles before and after intravitreal ranibizumab (IVR) treatment, 12 vitreous humor (VH) samples were collected from 6 proliferative diabetic retinopathy (PDR) patients before (pre group) and after IVR treatment (post group). LC–MS/MS and bioinformatics analysis...

ORGANISM(S): Homo sapiens (Human)

2022-08-12 | PXD027592 | Pride

Proliferative diabetic retinopathy proteomics ranibizumab label-free lc–ms/ms prm

Change of Ranibizumab-induced Human Vitreous Protein Profile in Patients with Proliferative Diabetic Retinopathy Based on Proteomics Analysis

Background: Preoperative treatment of anti-vascular endothelial growth factor (VEGF) agents is extensively used in proliferative diabetic retinopathy (PDR), but the molecular mechanism is not fully understood. The objective of this research is to observe change of protein profile induced by Ranibizu...

ORGANISM(S): Homo sapiens (Human)

2018-10-19 | PXD008901 | Pride

Proteomics proliferative diabetic retinopathy ranibizumab

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