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ModelsEftimie2018 - Cancer and Immune biomarkers
The paper describes a model on the detection of cancer based on cancer and immune biomarkers. Created by COPASI 4.25 (Build 207) This model is described in the article: Improving cancer detection through combinations of cancer and immune biomarkers: a modelling approach Raluca Eftimie and and E...
2024-09-02 | BIOMD0000000741 | BioModels
Immuno-oncology 
ProteomicsSystematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers
Background: Preeclampsia (PE) is a hypertensive disorder of pregnancy with various clinical symptoms. However, traditional markers for the disease including high blood pressure and proteinuria are poor indicators of the related adverse outcomes. Here, we performed systematic proteome profiling of pl...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD050118 | Pride
Proteomics Plasma Preeclampsia Human 
ProteomicsIdentifying fecal host biomarkers for the presence and severity of Clostridioides difficile infection using top-down proteomics
Clostridioides difficile is a major cause of healthcare-associated diarrhea in adult patients. Laboratory diagnosis of C. difficile infection (CDI) is challenging as there is no single test combining high sensitivity and specificity, rapid turnaround time and cost efficiency. They also offer no or l...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020117 | Pride
Matrix metalloproteinase-7 Mass spectrometry Human Immunoglobulin kappa constant Biomarker discovery Free immunoglobulin light chain Stool Clostridium difficile Mouse model Proteomics Alpha-2-macroglobulin Feces Alpha-1-antitrypsin Clostridioides difficile 
TranscriptomicsMultiple Salivary Biomarkers for Early Detection of Pancreatic Cancer
Pancreatic cancer is the fourth leading cause of cancer death. Lack of early detection technology for pancreatic cancer invariably leads to a typical clinical presentation of incurable disease at initial diagnosis. Oral fluid (saliva) meets the demand for non-invasive, accessible, and highly efficie...
ORGANISM(S): Homo sapiens 
2008-12-30 | E-GEOD-14245 | biostudies-arrayexpress
TranscriptomicsPancreatic cancer biomarkers in mouse saliva
This is a pilot study. We are trying to detect potential salivary biomarkers in mice with a pancreatic tumor. Global gene expression profiling has shown great promise in high-throughput biomarker discovery for early disease detection in body fluids such as saliva, which is accessible, cost-effectiv...
ORGANISM(S): Mus musculus 
2013-06-12 | E-GEOD-47811 | biostudies-arrayexpress
ProteomicsA novel approach for the discovery of biomarkers of radiotherapy response in breast cancer
Radiotherapy is a commonly used treatment modality for the local control of breast cancer. However, the clinical signs of radiotherapy response are often not apparent for several weeks post-treatment. We currently lack tools to predict and/or monitor tumor responses during treatment. The aim of this...
ORGANISM(S): Homo sapiens (Human) 
2021-08-13 | PXD027572 | Pride
Radiosensitivity biomarkers Human breast cancer Secretome Radiotherapy Radioresistance 
ProteomicsQuantitative label-free proteomic analysis of human urine to identify novel protein biomarkers for schistosomiasis
Background: Schistosomiasis is a chronic neglected tropical disease that is characterized by continued inflammatory challenges to the exposed population, and it has been established as a possible risk factor in the aetiology of bladder cancer. Improved diagnosis of schistosomiasis and its associated...
ORGANISM(S): Homo sapiens (Human) Schistosoma haematobium 
2017-10-24 | PXD006438 | Pride
Schistosoma haematobium Bladder cancer Discovery proteomics Qexactive Schistosomiasis Biomarkers 
TranscriptomicsSearch for specific biomarkers of IFN-beta bioactivity in patients with MS
We aimed to identify specific biomarkers of IFN-beta bioactivity in order to compare their gene expression induction by type I IFNs with the MxA, and to investigate their potential role in MS pathogenesis. Gene expression microarrays were performed in PBMC from MS patients who developed neutralizing...
ORGANISM(S): Homo sapiens 
2010-12-18 | E-GEOD-26104 | biostudies-arrayexpress
GenomicsBiomarkers in older ovarian cancer patients
Biomarkers in older ovarian cancer patients
PRJNA521520 | ENA
ProteomicsSerum quantitative proteomics identifies prognostic biomarkers and physiological processes related to COVID-19 symptomatology
The coronavirus disease 19 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) posts a challenge for the understanding of factors affecting disease severity and the identification of prognostic biomarkers and physiological processes relevant for the development...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD024549 | Pride
Swath-ms Human serum Covid-19 
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