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ProteomicsCharacterization of serine proteases from Canavalia ensiformis leaf
Serine proteases has been vastly reported to be found (and identified) only in seed extracts of Canavalia ensiformis (C. ensiformis), however, our group observed expressive serine protease activities in aqueous extracts from leaves, seeds, roots, and stem, especially in a leaf extract obtained with ...
ORGANISM(S): Canavalia ensiformis 
2020-08-28 | PXD010569 | Pride
Serine proteases Canavalia ensiformis Purification 
ProteomicsHTPS screen of coagulation proteases at 20C with NaCl, ChCl, LiCl
Goal of the experiment is the characterization of proteases activity and specificity upon Na+ binding. Na+ is an allosteric binders that can induce a conformational change of the protease AS to regulate activity and specificity; only proteases with Y and F in position 225 can coordinate a Na+ molecu...
ORGANISM(S): Homo sapiens (Human) 
2021-02-04 | PXD022959 | Pride
Protease investigation 
GenomicsEffect of proteases on soil
Effect of proteases on soil: Bioestimulation and Microbial Biodiversity
PRJEB35654 | ENA
TranscriptomicsTranscriptional profiling of an HtrA proteases knock-out compared to wild type
Transcriptional profiling of an HtrA proteases knock-out compared to wild type on two different time points; logarithmic growth phase and stationary growth phase 3 Biological replicates per time point, two arrays
ORGANISM(S): Peptoclostridium difficile 
2014-08-02 | E-GEOD-55926 | biostudies-arrayexpress
ProteomicsMapping specificity, entropy, allosteric changes and substrates in blood coagulation proteases by a high-throughput protease screen
Proteases are crucial physiologic regulators of protein structure and function. While proteomic methods contributed extensively to protease characterization efforts, technical challenges remain in terms of throughput, scalability and large datasets of protease cleavages remain scarce. Here, we descr...
ORGANISM(S): Homo sapiens (Human) 
2021-02-05 | PXD018976 | Pride
High-throughput protease screen Substrates Blood coagulation proteases Specificity Entropy Allostery 
ProteomicsGenomic Survey of Aspergilli Proteases
We have performed a combined analysis of comparative genomics, proteomics and enzymology tests on seven Aspergillus species grown on wheat bran and sugar beet pulp to identify the various proteases and their productivities in Aspergilli.
ORGANISM(S): Aspergillus niger Aspergillus flavus Aspergillus terreus Aspergillus oryzae var. oryzae Neosartorya fischeri Aspergillus fumigatus Af293 Emericella nidulans (Aspergillus nidulans) 
2017-01-04 | PXD000982 | Pride
Aspergillus Proteases Secretome 
ProteomicsProtease activity profiling of ovarian clear cell carcinoma
Ovarian clear cell carcinoma (OCCC) is an understudied poor prognosis subtype of ovarian cancer lacking in effective molecularly targeted therapies; efforts to define drivers of OCCC malignancy may lead to new therapeutic targets and approaches. Among potential targets are secreted proteases, enzyme...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-05-07 | MSV000087385 | MassIVE
GenomicsPlasticity in AAA+ proteases reveals substrate specificity niches
Plasticity in AAA+ proteases reveals substrate specificity niches
PRJNA701919 | ENA
TranscriptomicsCritical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes.
Abstract
BACKGROUND: Gene expression profiling (GEP) in cells obtained from peripheral blood has demonstrated to be a very useful approach for biomarker discovery and for studying molecular pathogenesis of prevalent diseases. While there is limited literature availble on gene expression markers a...
ORGANISM(S): Homo sapiens 
2013-03-12 | E-MEXP-3589 | biostudies-arrayexpress
UnknownMembrane-anchored serine proteases as regulators of epithelial function.
Not available
S-EPMC9869603 | biostudies-literature
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