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GenomicsRNA-seq: WT under proteotoxic stress conditions
RNA-seq: WT under proteotoxic stress conditions
PRJNA510953 | ENA
TranscriptomicsSearching for the fusion transcripts created during proteotoxic stress
To verify the hypothesis that proteotoxic stress induces the formation of fusion transcripts in non-cancerous and cancerous cells derived from breast epithelium, we exposed the cells to heat shock (HS, 1h at 43 degrees). We selected MCF10A non-tumorigenic breast epithelial cells (isolated from the m...
ORGANISM(S): Homo sapiens 
2024-12-01 | E-MTAB-13903 | biostudies-arrayexpress
Transcriptomicsheat shock SUMO-2 RNA-seq
RNA-seq analysis of poly-A RNA from untreated U2OS cells, and from U2OS cells exposed to heat stress (43 C) for 4 hours
ORGANISM(S): Homo sapiens 
2015-07-15 | E-MTAB-2349 | biostudies-arrayexpress
GenomicsThe Lon protease links nucleotide metabolism with proteotoxic stress
The Lon protease links nucleotide metabolism with proteotoxic stress
PRJNA639285 | ENA
ProteomicsRibosomal protein deficiency generates proteotoxic stress that is alleviated by TOR inhibition
Ribosomes are multi-component molecular machines that synthesize all the proteins of living cells. Understandably, most genes encoding the protein components of ribosomes are essential. Reduction in gene dosage is often viable but deleterious and associated with human syndromes, collectively known a...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-01-14 | PXD023021 | Pride
Eif2 Protein translation Diamond blackfan anemia Ribosomes Autophagy Rps23 Ribosomopathies Protein aggregates Tor Proteotoxic stress Apoptosis P62 Rps26 
GenomicsThe integrated stress response protects microtubule dynamics to recover from proteotoxic stress
The integrated stress response protects microtubule dynamics to recover from proteotoxic stress
PRJNA798445 | ENA
GenomicsEffect of peroxisomal proteotoxic stress on gene expression in mammalian cells
Effect of peroxisomal proteotoxic stress on gene expression in mammalian cells
PRJNA933278 | ENA
GenomicsProteotoxic stress-induced apoptosis in cancer cells: understanding the susceptibility and enhancing the potency
Proteotoxic stress-induced apoptosis in cancer cells: understanding the susceptibility and enhancing the potency
PRJNA846688 | ENA
UnknownProteotoxic Stress as an Exploitable Vulnerability in Cells with Hyperactive AKT.
Not available
S-EPMC8583472 | biostudies-literature
TranscriptomicsStress-dependent CHIP/Daxx interaction suppresses the p53 apoptotic program
Our previous studies have implicated CHIP as a co-chaperone/ubiquitin ligase, whose activities yield protection against stress-induced apoptotic events. In this report, we demonstrate a stress-dependent interaction between CHIP (carboxyl terminus of Hsp70-interacting protein) and Daxx, death domain-...
ORGANISM(S): Mus musculus 
2010-04-03 | E-GEOD-14339 | biostudies-arrayexpress
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