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MetabolomicsAdaptive laboratory evolution of microbial co-cultures for improved metabolite secretion

Adaptive laboratory evolution has proven highly effective for obtaining microorganisms with enhanced capabilities. Yet, this method is inherently restricted to the traits that are positively linked to cell fitness, such as nutrient utilization. Here, we introduce coevolution of obligatory mutuali...

2021-07-02 | MTBLS2217 | MetaboLights
MetabolomicsTranscriptomic dynamics control rapid transition of core crop functions in 'lactating' pigeon

Pigeons (Columba livia) are widely kept as domesticated pets worldwide, and may have adapted to captivity through the evolutionarily specialized ability to produce ‘milk’ in the crops of both male and female parents via rapid proliferation and shedding of lipid- and protein-enriched epithelial ce...

2023-02-13 | MTBLS5195 | MetaboLights
MetabolomicsRapid detection of Staphylococcus aureus and Streptococcus pneumoniae by real-time analysis of volatile metabolites
Early detection of pathogenic bacteria is needed for rapid diagnostics allowing adequate and timely treatment of infections. In this study, we show that Secondary Electro-Spray Ionization-High Resolution Mass Spectrometry (SESI-HRMS) can be used as a diagnostic tool for rapid detection of bacterial ...
2022-07-06 | MTBLS5085 | MetaboLights
TranscriptomicsRapid evolution of phenotypic plasticity and shifting thresholds of genetic assimilation in the nematode Caenorhabditis remanei
Many organisms can acclimate to new environments through phenotypic plasticity, a complex trait that can be heritable, subject to selection, and evolve. However, the rate and genetic basis of plasticity evolution remain largely unknown. We experimentally evolved outbred populations of the nematode C...
ORGANISM(S): Caenorhabditis remanei 
2014-05-04 | E-GEOD-56510 | biostudies-arrayexpress
TranscriptomicsBP001-002: The genomic landscape of compensatory evolution
Adaptive evolution is generally assumed to progress through the accumulation of beneficial mutations. However, deleterious mutations may also have an important role by promoting adaptive genetic changes that are otherwise inaccessible. Here we study the capacity of the bakerM-bM-^@M-^Ys yeast genome...
ORGANISM(S): Saccharomyces cerevisiae BY4741 
2014-08-27 | E-GEOD-55373 | biostudies-arrayexpress
ProteomicsRapid adaption but genetic diversity loss of a globally distributed diatom in the warmer ocean
Studies have demonstrated that marine phytoplankton can adapt to the warmer environment. However, the underlying mechanisms remain largely unknown. Here, we quantified the capacity of a globally distributed marine diatom Skeletonema dohrnii, for rapid evolution under the moderate (24 ℃) and severe (...
ORGANISM(S): Skeletonema Dohrnii 
PXD057232 |
TranscriptomicsRNA-seq of 6 tissues from 10 species to investigate the evolution of gene expression levels in mammalian organs
Changes in gene expression are thought to underlie many of the phenotypic differences between species. However, large-scale analyses of gene expression evolution were until recently prevented by technological limitations. Here we report the sequencing of polyadenylated RNA from six organs across ten...
ORGANISM(S): Gallus gallus 
2011-10-12 | E-GEOD-30352 | biostudies-arrayexpress
GenomicsPool sequencing of rapid evolution of Arabidopsis thaliana populations
Monitoring rapid evolution of plant populations at scale with Pool-Sequencing
PRJEB53572 | ENA
TranscriptomicsEvolution of human-specific microRNA miR-941 [cerebellum gene expression]
miRNA-mediated gene expression silencing has previously been shown to be important for a variety of physiological and pathological processes. Here, we have explored the role of one bona fide human-specific miRNA (miR-941) in evolution of the human-specific expression and function. Using combination ...
ORGANISM(S): Homo sapiens 
2012-12-20 | E-GEOD-35619 | biostudies-arrayexpress
GenomicsConserved Function of lincRNAs in Vertebrate Embryonic Development Despite Rapid Sequence Evolution
Thousands of large intervening non-coding RNAs (lincRNAs) have been identified in mammals. To better understand the evolution and functions of these enigmatic RNAs, we used chromatin marks, poly(A)-site mapping and RNA-Seq data, to identify more than 550 distinct lincRNAs in zebrafish. Although thes...
ORGANISM(S): Danio rerio 
2011-12-22 | E-GEOD-32880 | biostudies-arrayexpress
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