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ProteomicsProteome changes in retinal Mueller glial cells from a spontaneous equine model for autoimmune uveitis compared to healthy controls
Retinal Müller glial cells (RMG) play a central role in retinal neuroinflammation, actively participating in the immune response and adopting a dynamic inflammatory phenotype. However, the precise functions of RMG in retinal inflammation remain incompletely understood. In this study, we investigated...
ORGANISM(S): Equus caballus (Horse) 
2025-05-07 | PXD058170 | Pride
Quantitative label-free lc-ms/ms  retinal neuroinflammation  autoimmune uveitis  equine recurrent uveitis (eru)  spontaneous equine animal model  retinal mueller glial cells (rmg) 
ProteomicsEarly retinal synaptic dysfunction and proteomic remodeling precede neurodegeneration in a Parkinson’s disease model
Parkinson’s disease (PD) affects motor and non-motor systems, but retinal changes and their molecular basis are not well understood. Using a transgenic mouse model overexpressing A53T-mutant human α-synuclein, we examined retinal function, structure, and proteomics at 6 and 16 months. Early retinal ...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-23 | PXD066087 | Pride
Visual dysfunction Retina Parkinson's disease Proteomics 
UnknownAdenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure.
Not available
S-EPMC4465153 | biostudies-literature
UnknownLipoxins A4 and B4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation.
Not available
S-EPMC10782675 | biostudies-literature
UnknownEmpagliflozin targets Mfn1 and Opa1 to attenuate microglia-mediated neuroinflammation in retinal ischemia and reperfusion injury.
Not available
S-EPMC10714482 | biostudies-literature
UnknownFerulic acid attenuates microglia-mediated neuroinflammation in retinal degeneration.
Not available
S-EPMC7789661 | biostudies-literature
TranscriptomicsNeuroinflammation in Advanced Canine Glaucoma
Dogs frequently develop glaucoma, a disease that leads to vision loss due to loss of retinal ganglion cells and degeneration of axons within the optic nerve. We used Affymetrix Gene chips to characterize transcriptional changes between healthy and glaucomatous retinas. These data describe gene expr...
ORGANISM(S): Canis lupus familiaris 
2010-10-06 | E-GEOD-21879 | biostudies-arrayexpress
UnknownValproic Acid Reduces Neuroinflammation to Provide Retinal Ganglion Cell Neuroprotection in the Retina Axotomy Model.
Not available
S-EPMC9135180 | biostudies-literature
UnknownPathological high intraocular pressure induces glial cell reactive proliferation contributing to neuroinflammation of the blood-retinal barrier via the NOX2/ET-1 axis-controlled ERK1/2 pathway.
Not available
S-EPMC11034147 | biostudies-literature
UnknownATF3 prevents retinal ganglion cell apoptosis and mitigates microglia-mediated neuroinflammation in retinal ischemia-reperfusion injury.
Not available
S-EPMC12571733 | biostudies-literature
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