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This dataset contains LC-MS/MS-based proteomic data generated from muscle/myoseptal tissues of wild-type, heterozygous runx2b mutant, and homozygous runx2b mutant Culter alburnus individuals. The study aimed to characterize proteomic changes associated with runx2b-mediated intermuscular bone reducti...
ORGANISM(S): Culter alburnus 
2026-09-07 | PXD080591 | Pride
Integrated transcriptomic and proteomic analysis reveals Runx2b-associated molecular regulation of intermuscular bone development in Culter alburnus
This study investigated transcriptomic changes associated with runx2b-mediated regulation of intermuscular bone development in Culter alburnus. Bulk RNA-seq was performed on muscle/myoseptal region samples from wild-type, runx2b heterozygous mutant, and runx2b homozygous mutant juveniles. The datase...
ORGANISM(S): Culter alburnus 
2026-08-05 | GSE337778 | GEO
Single-cell transcriptomes and runx2b−/− mutants reveal the genetic signatures of intermuscular bone formation in teleosts
Purpose: Intermuscular bones (IBs) are hard spicules, mainly existing in the myosepta of recent vertebrates. This evolutionary trait has puzzled biologists and consumers, and the molecular basis of IB development remains unclear. The goals of this study are to acquire characteristic single-cell maps...
ORGANISM(S): Danio rerio 
2021-11-04 | GSE186957 | GEO
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