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ProteomicsA proteomic view of WT and △ydiV(stm1344) Salmonella Typhimurium in simulated host environment medium
The flagellum provides essential motility in the pathogenic process of Salmonella host invasion. However, flagellin is strongly antigenic and can be recognized by TLR5, resulting in activation of the host immune system to clear the invading pathogen. The presence of flagella also disrupts the integr...
ORGANISM(S): Escherichia coli 
2022-10-12 | PXD035693 | Pride
Differential protein expression  simulated host environment medium  wt and △ydiv 
TranscriptomicsMycobacterium avium subsp. paratuberculosis gene transcription in simulated phagosomal environment and in human macrophage infection
This SuperSeries is composed of the following subset Series: GSE32241: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro acid-nitrosative multi-stress GSE32242: Differentially regulated genes induced in Mycobacterium avium subspecies paratuberculos...
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2012-05-31 | E-GEOD-32243 | biostudies-arrayexpress
TranscriptomicsDifferentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line
Transcriptional profile of Mycobacterium avium subspecies paratuberculosis in in vitro THP-1 (ATCC TIB-202) cell line infection, comparing bacteria grown in host medium and intracellular bacteria recovered from infected THP-1 cells. Two-condition experiment, MAP-K vs. intracellular MAP-THP-1. Biolog...
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2012-05-31 | E-GEOD-32242 | biostudies-arrayexpress
ProteomicsChanges in OMPs of Leptospira under simulated physiological conditions of infection
Leptospirosis is a worldwide zoonotic disease caused bypathogenic Leptospiraspread through urine of infected animals. There are many gaps in understanding the pathophysiology of leptospirosis and the host immunity.This lack of knowledge hinders taking necessary steps in the development of a potentia...
ORGANISM(S): Leptospira interrogans serovar Icterohaemorrhagiae 
2025-09-08 | PXD035782 | Pride
Proteomics Pathogenic Leptospira 
TranscriptomicsTranscriptome analysis of three Bacillus cereus strains comparing non-conditioned growth medium (nk) with conditioned (k; pre-incubated with CaCo-2 cells), accomplished by RNA sequencing
Enteropathogenic Bacillus cereus can cause toxico-infections manifesting in diarrhea and abdominal pain. It is still not completely understood why individual isolates differ in enterotoxin production and pathogenicity, and which signals trigger toxicity in the host environment. The overall transcrip...
ORGANISM(S): Bacillus cereus 
2026-08-01 | GSE284237 | GEO
GenomicsTranscriptome analysis of three Bacillus cereus strains comparing non-conditioned growth medium (nk) with conditioned (k pre-incubated with CaCo-2 cells), accomplished by RNA sequencing
Transcriptome analysis of three Bacillus cereus strains comparing non-conditioned growth medium (nk) with conditioned (k pre-incubated with CaCo-2 cells), accomplished by RNA sequencing
PRJNA1198047 | ENA
TranscriptomicsDifferentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro acid-nitrosative multi-stress
Transcriptional profile of Mycobacterium avium subspecies paratuberculosis in in vitro acid-nitrosative multistress, comparing untreated control cells and bacteria under multi-stress. Two-condition experiment, MAP-K vs. MAP-ACID-NO treated. Biological replicates: 3 controls, 3 Acid-NO treated, indep...
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2012-05-31 | E-GEOD-32241 | biostudies-arrayexpress
UnknownPeptidomics Analysis of Virulent Peptides Involved in Streptococcus suis Pathogenesis.
Not available
S-EPMC8468194 | biostudies-literature
TranscriptomicsIdentification of genes regulated by gadE in E. coli O157:H7
Integrating laterally acquired virulence genes into the backbone regulatory network is important for the pathogenesis of Escherichia coli O157:H7, which has captured many virulence genes through horizontal transfer during evolution. GadE is an essential transcriptional activator of glutamate decarbo...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-13132 | biostudies-arrayexpress
TranscriptomicsTranscriptional and proteomic response of Pseudomonas aeruginosa PAO1 to spaceflight conditions involves Hfq regulation and reveals a role for oxygen
Characterization of bacterial behavior in the microgravity environment of spaceflight is of importance towards risk assessment and prevention of infectious disease during long-term missions. Further, this research field unveils new insights into connections between low fluid-shear regions encountere...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2011-06-28 | E-GEOD-22684 | biostudies-arrayexpress
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