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GenomicsMatrix stiffness regulates telocyte differentiation into fibroblasts in vitro
Matrix stiffness regulates telocyte differentiation into fibroblasts in vitro
PRJNA1295943 | ENA
TranscriptomicsMatrix stiffness regulates telocyte differentiation into fibroblasts in vitro
Primary telocytes from ankle joints of Efhd1CreER x Ai9 mice were purified by FACS based on tdTomato (tdT) expression. These tdT⁺ telocytes were cultured on collagen-coated CytoSoft® plates of varying stiffness (0.2, 8, and 64 kPa). After 24 hours, cells were harvested for bulk RNA sequencing using ...
ORGANISM(S): Mus musculus 
2026-02-13 | GSE303624 | GEO
GenomicsThe developmental emergence and stem cell-based renewal of the intestinal telocyte niche
The developmental emergence and stem cell-based renewal of the intestinal telocyte niche
PRJNA1063358 | ENA
TranscriptomicsThe developmental emergence and stem cell-based renewal of the intestinal telocyte niche
The intestinal telocytes that reside beneath the intestinal epithelium exert niche-supporting roles for intestinal stem cells (ISCs) and their progenies. They are heterogenous cells compartmentalized along the crypt-villus axis, but the lineage relationships and mechanisms governing the maintenance ...
ORGANISM(S): Mus musculus 
2025-08-19 | GSE252975 | GEO
UnknownRegulatory roles of Osteopontin in lung epithelial inflammation and epithelial-telocyte interaction.
Not available
S-EPMC10442477 | biostudies-literature
TranscriptomicsscRNA-seq reveals transcriptional profiling of telocytes in synovial tissue
This study employs scRNA-seq to characterize Efhd1⁺ tdTomato⁺ telocyte-like cells isolated from knee synovial tissues. By comparing their transcriptional profiles to fibroblasts, we aim to delineate distinct cellular phenotypes and understand telocyte heterogeneity across tissue microenvironments. O...
ORGANISM(S): Mus musculus 
2026-02-13 | GSE303999 | GEO
UnknownThe Function of <i>Efhd1</i> <sup>+</sup> Telocytes in the Synovial Lymphatic System and Inflammatory-Erosive Arthritis.
Not available
S-EPMC12637515 | biostudies-literature
UnknownInfluence of gene modification in biological behaviors and responses of mouse lung telocytes to inflammation.
Not available
S-EPMC6521571 | biostudies-literature
UnknownThe Role of Telocytes and Telocyte-Derived Exosomes in the Development of Thoracic Aortic Aneurysm.
Not available
S-EPMC9099883 | biostudies-literature
TranscriptomicsSpatial mapping of telocytes along the crypt-villus axis reveals their role in intestinal homeostasis
We employed a single-cell RNA sequencing approach using the 10X Genomics platform to study the diversity of telocyte populations in the mouse jejunum. Telocytes are a unique mesenchymal cell type expressing the transcription factor Foxl1 and forming a subepithelial network along the entire crypt-vil...
ORGANISM(S): Mus musculus 
2026-06-01 | GSE297695 | GEO
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