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TranscriptomicsPlant toxin treatment of neonatal mouse cholangiocytes
Extrahepatic bile ducts were isolated from mouse pups at days 0-3 and primary cholangiocytes were isolated. Cholangiocytes were treated with DMSO, bilatresone (TOX4), betavulgarin (TOX2), and isoflavanone (TOX3), as per Lorent et al, Science Translationa Medicine 2015;286:286ra67 (Fig. 1), all in DM...
ORGANISM(S): Mus musculus 
2020-01-01 | GSE136895 | GEO
GenomicsPlant toxin treatment of neonatal mouse cholangiocytes
Plant toxin treatment of neonatal mouse cholangiocytes
PRJNA564001 | ENA
UnknownA novel functional variant in 8q24 is associated with regulation of prostate stem cell antigen (PSCA) gene expression and bladder cancer risk
Not available
S-EPMC3439080 | biostudies-literature
UnknownCoping Using Sex During the Coronavirus Disease 2019 (COVID-19) Outbreak in the United Kingdom.
Not available
S-EPMC7691167 | biostudies-literature
ProteomicsMammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression
Histone acetylation is widely assumed to directly instruct gene activation. Among acetylated residues, H4K16ac is one of the most abundant modifications, conserved across all eukaryotes. Here we analyzed histone PTM profiles in MSL KO and HDAC inhibitor-treated cells.
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD066155 | Pride
Histone post translationa modification H4k16ac 
ProteomicsComparison of in-gel digestion methods for histone PTM analysis
In order to optimize the histone digestion procedure for low-abundance clinical samples, we compared different in-gel digestion protocols. Histones are usually digested in-gel using “Arg-C-like” strategies, which involve chemical acylation of lysines followed by trypsin digestion (17). Acylated lysi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD024745 | Pride
Epigenetics Histone post-translationa modification 
ProteomicsHistone PTM analysis in breast cancer cells treated with methyltransferase inhibitors
Histone PTM analysis were analyzed in breast cancer cells treated with methyltransferase inhibitors.
ORGANISM(S): Homo sapiens (Human) 
2025-08-01 | PXD064421 | Pride
Histone post-translationa modifications Methyltransferase inhibitors 
ProteomicsTherapy-Induced Senescence Promotes Immunogenicity in Acute Myeloid Leukaemia Blasts through loss of PRC2-Mediated Gene Regulation
We employed mass spectrometry to perform an unbiased, quantitative analysis of histone modifications in newly diagnosed AML patients stratified by senescence competency
ORGANISM(S): Homo sapiens (Human) 
2026-08-07 | PXD065846 | Pride
Histone post-translationa modifications Acute myeloid leukaemia 
UnknownCardiovascular Implications of the COVID-19 Pandemic: A Global Perspective.
Not available
S-EPMC7229739 | biostudies-literature
ProteomicsQuantitative proteomics of Col and AtPABs mutant
To determine if the difference in AtPAB-binding efficiency affects protein levels, we performed the Tandem Mass Tag (TMT)-based quantitative proteomics on the two-week old seedlings of Col and the mut, respectively.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-10-11 | PXD014071 | Pride
Poly(a)-binding proteins  binding efficiency  translationa  arabidopsis 
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