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The small genome of polyomaviruses encodes a limited number of proteins that are highly dependent on interactions with host cell proteins for efficient viral replication. The SV40 large T antigen (LT) contains several discrete functional domains that contribute to the viral life cycle, including the...
ORGANISM(S): Homo sapiens 
To measure on a global scale the SV40 large T antigen-mediated changes in gene transcription in mouse embryo fibroblasts differing in the expression of p53. Samples of total RNA from 3T3 (wt p53) and 10-1 (p53-null) mouse embryo fibroblasts stably transfected with SV40 large T-antigen expressing pMY...
ORGANISM(S): Mus musculus 
One of our previous studies has shown that there are two IgY subclasses (termed IgY1 and IgY2) in the serum of snake Elaphe taeniura, and both subclasses are expressed as full-length and shortened isoforms (IgY1-L, IgY2-L,IgY1-S, and IgY2-S). Using 2-DE and LC-MS/MS, we detected IgY1-L, IgY2-L,IgY1-...
ORGANISM(S): Elaphe Taeniura 
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