unexplained male infertility

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New insights on sperm function in male infertility of unknown origin: proteomics characterization

The global trend on (male)infertility is concerning and the unidentifiable causes in half of the cases demands a better understanding of the molecular, biochemical and metabolic mechanisms as well as the identification of external and internal factors operating behind it, that might help to explain ...

ORGANISM(S): Homo sapiens (Human)

2024-02-28 | PXD040292 | Pride

Alterations in the abundance of protamine proteoforms related to sperm chromatin packaging, obesity, and age in men with unexplained infertility

Protamine1 (P1) and Protamine 2 family (P2) are the most relevant nuclear proteins in the male gamete since are necessary to compact and protect the paternal genome. Human and mouse sperm contain a complex population of protamine proteoforms, which raises the interest to decipher whether it responds...

ORGANISM(S): Homo sapiens (Human)

2025-04-25 | PXD049367 | Pride

Proteoforms Top-down proteomics Protamines Male infertility Sperm Chromatin

Sperm centriole assessment identifies male factor infertility in couples with unexplained infertility - a pilot study.

Not available

S-EPMC9692136 | biostudies-literature

Efficacy of Antioxidant Supplementation on Conventional and Advanced Sperm Function Tests in Patients with Idiopathic Male Infertility.

Not available

S-EPMC7139646 | biostudies-literature

Is There a Relevant Clinical Impact in Differentiating Idiopathic versus Unexplained Male Infertility?

Not available

S-EPMC10042653 | biostudies-literature