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TranscriptomicsMicroRNA profiling of human cancer cells after treatment with the chromatin modifying drugs 5-aza-2 deoxycytidine and 4-phenylbutyric acid
miRNA expression profiling in human cancer cells after 5-aza-2'-deoxycytidine and 4-phenylbutyric acid treatment to investigate whether microRNA expression is controlled by these chromatin modifying drugs.
ORGANISM(S): Homo sapiens 
2005-01-01 | E-MEXP-706 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling of human gastric cancer cells after treatment with 5-aza-2-deoxycytidine and 4-phenylbutyric acid
microRNA expression profiling in gastric cancer cells after 5-aza-2'-deoxycytidine (5-Aza-CdR) and 4-phenylbutyric acid (PBA) treatment was performed to investigate whether microRNA expression is controlled by these chromatin modifying drugs.
ORGANISM(S): Homo sapiens 
2008-10-10 | E-MEXP-1820 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human gastric cancer cells after treatment with 5-aza-2-deoxycytidine and 4-phenylbutyric acid
Gene expression profiling in human gastric cancer cells after 5-aza-2'-deoxycytidine (5-Aza-CdR) and 4-phenylbutyric acid (PBA) treatment was analyzed to investigate what genes are controlled by these chromatin modifying drug
ORGANISM(S): Homo sapiens 
2008-10-09 | E-MEXP-1821 | biostudies-arrayexpress
UnknownQuantification of the Chemical Chaperone 4-Phenylbutyric Acid (4-PBA) in Cell Culture Media via LC-HRMS: Applications in Fields of Neurodegeneration and Cancer.
Not available
S-EPMC9960049 | biostudies-literature
Genomics4-Phenylbutyric Acid Activates an NF-κB - Egr-1 Axis to Control Myoblast Proliferation and ECM Gene Expression Profiles
4-Phenylbutyric Acid Activates an NF-κB - Egr-1 Axis to Control Myoblast Proliferation and ECM Gene Expression Profiles
PRJNA1398260 | ENA
Transcriptomics4-Phenylbutyric Acid Activates an NF-κB - Egr-1 Axis to Control Myoblast Proliferation and ECM Gene Expression Profiles
Myoblasts are proliferative precursors derived from satellite cells and play critical roles in skeletal muscle growth, regeneration, and repair. The transition from myoblast proliferation to differentiation is tightly controlled by epigenetic mechanisms, particularly histone acetylation. During myog...
ORGANISM(S): Mus musculus 
2026-01-21 | GSE315556 | GEO
Unknown4-Phenylbutyric Acid (4-PBA) Derivatives Prevent SOD1 Amyloid Aggregation In Vitro with No Effect on Disease Progression in SOD1-ALS Mice.
Not available
S-EPMC9409193 | biostudies-literature
ProteomicsProteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: new therapeutic targets.
Polycystic liver disease (PLD) is a group of genetic disorders characterized by bile duct dilatation and/or progressive development of multiple intrahepatic fluid-filled biliary cysts (>10), which are the main cause of morbidity. Current surgical and/or pharmacological therapies exert short-term and...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2020-05-25 | PXD017587 | Pride
Human and rat cholangiocytes Endoplasmic reticulum stress (er stress) 4-phenylbutyric acid (4-pba) Whole cell extracts Tims-tof pasef Polycystic liver disease (pld) Peaksq Perseus. Proteostasis 
TranscriptomicsmicroRNA expression signatures in colorectal cancer cell lines with demethylating treatment
To screen for epigenetically silenced miRNAs, wecarried out miRNA microarray analysis in three colorectal cancer (CRC) cell lines (HCT116, DLD-1 and RKO) treated with or without 5-aza-2'-deoxycytidine (aza). HCT116 and RKO cells were also treated with aza plus 4-phenylbutyric acid (PBA). In additi...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-29900 | biostudies-arrayexpress
UnknownA Colon-Targeted Prodrug, 4-Phenylbutyric Acid-Glutamic Acid Conjugate, Ameliorates 2,4-Dinitrobenzenesulfonic Acid-Induced Colitis in Rats.
Not available
S-EPMC7558321 | biostudies-literature
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