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ProteomicsProteomic profile of Cephalosporin-Resistant Neisseria gonorrhoeae Isolates by low pH nano-HPLC-MS/MS
The experiment was performed using three N. gonorrhoeae clinical isolates and N. gonorrhoeae strain ATCC 49226 was used as a reference strain. Tandem mass spectra were processed by PEAKS Studio version 8.5 (Bioinformatics Solutions Inc., Waterloo, Canada). PEAKS DB was set up to search the database ...
ORGANISM(S): Neisseria gonorrhoeae 
2019-10-22 | PXD015296 | Pride
Low ph nano-hplc-ms/ms  cephalosporin-resistant neisseria gonorrhoeae 
ProteomicsForebrain proteome of mangrove rivulus fish in different behavioral contexts
The forebrain proteome of mangrove rivulus was determined in fish with different social behavior patterns. All fish were from and all experiments done in Professor Ryan Earley's Laboratory at the University of Alabama. Label-free quantitative proteomics was performed using Top3 (PEAKSQ) and spectral...
ORGANISM(S): Kryptolebias Marmoratus (ncbitaxon:37003) 
2018-08-08 | MSV000082806 | MassIVE
ProteomicsProteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: new therapeutic targets.
Polycystic liver disease (PLD) is a group of genetic disorders characterized by bile duct dilatation and/or progressive development of multiple intrahepatic fluid-filled biliary cysts (>10), which are the main cause of morbidity. Current surgical and/or pharmacological therapies exert short-term and...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2020-05-25 | PXD017587 | Pride
Human and rat cholangiocytes Endoplasmic reticulum stress (er stress) 4-phenylbutyric acid (4-pba) Whole cell extracts Tims-tof pasef Polycystic liver disease (pld) Peaksq Perseus. Proteostasis 
ProteomicsQuantitative proteomics reveals oxygen-induced adaptations in Caldalkalibacillus thermarum TA2.A1 chemostat cultures
Caldalkalibacillus thermarum possesses a highly branched respiratory chain. Branched electron transport chains (ETC) in model organisms such as Escherichia coli primarily facilitate growth at a wide range of dissolved oxygen levels. The aim of this study was to investigate whether a polyextremophile...
ORGANISM(S): Caldalkalibacillus thermarum TA2.A1 
2025-01-18 | PXD047466 | Pride
Shotgun proteomics Caldalkalibacillus thermarum Oxygen adaptation 
ProteomicsRhodosporidium toruloides haplotypes IFO0559 and IFO0880 rapamycin treatment
Comparison between control groups and rapamycin treatment of both haplotypes of Rhodosporidium toruloides.
ORGANISM(S): Rhodotorula toruloides 
2025-05-07 | PXD052386 | Pride
Rhodosporidium Rapamycin 
ProteomicsSalt stress in freshwater anaerobic methane-oxidizing archaea
Maider J. Echeveste Medrano and colleagues characterized the physiological and metabolic response of freshwater methanotrophic archaea to salt stress. The study performed metaproteomics, gene expression profiles and dedicated metabolomics to identify the pathways involved in the salt stress response...
ORGANISM(S): Candidatus Methanoperedens nitroreducens 
2024-07-17 | PXD048239 | Pride
Salt stress Methane-oxidizing archaea Shotgun proteomics Metaproteomics 
ProteomicsQuantitation of ATIs in Wheat by LC-MS/MS – iTRAQ
A selection of ATIs was silenced in the common wheat cultivar Bobwhite and durum wheat cultivar Svevo by RNAi and gene editing, respectively, in order to reduce the amounts of ATIs. The controls and silenced lines were analyzed after digestion to peptides by LC-MS/MS with different approaches to eva...
ORGANISM(S): Triticum aestivum (Wheat) Triticum durum 
2022-10-13 | PXD034478 | Pride
Amylase/trypsin inhibitor  wheat  crsipr-cas9  rnai 
ProteomicsAntimycin A-treated vs ETFDH-ko myoblasts TMT
The electron transfer flavoprotein dehydrogenase (ETFDH) is the bottleneck enzyme of fatty acid oxidation (FAO). We performed a TMT 6plex analysis on Antimycin A treated and ETFDH-ko myoblasts (compared to CRL).
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD045588 | Pride
Myoblast Tmt Etfdh Antimycin a 
ProteomicsProteome of systemic extracellular vesicles from sporadic and familiar Alzheimer’s disease
Evidence suggests that extracellular vesicles (EVs) act as mediators and biomarkers of neurodegenerative diseases. Two distinct forms of Alzheimer Disease (AD) are known: a late-onset sporadic form (SAD) and an early-onset familial form (FAD). This project aims to characterize and compare the protei...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021718 | Pride
Extracellular vesicles Plasma Sporadic and familiar alzheimer’s Lc-ms/ms 
ProteomicsTMT-Based Quantitative Proteomics of Cerebrospinal Fluid Reveals Molecular Signatures of Lymphatic Drainage Impairment in Young Rats
The glymphatic system facilitates the clearance of interstitial solutes and waste products from the brain parenchyma, channeling them into the meningeal lymphatic vessels for subsequent drainage into the deep cervical lymph nodes (dcLNs). However, the extent to which this lymphatic outflow via dcLNs...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-07-04 | PXD063564 | Pride
Dc-ln cauterization Csf 
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