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MetabolomicsExometabolomics of HK2, 786-O cells cultured in Plasmax media
Not available
ORGANISM(S): Homo sapiens 
ST002226 | MetabolomicsWorkbench
MetabolomicsCatabolism of branched-chain amino acids (BCAAs) in renal cells HK2 and 786-O
Not available
ORGANISM(S): Homo sapiens 
ST002220 | MetabolomicsWorkbench
TranscriptomicsExpression data from 786-O renal cell cancer cells treated with pentamidine
While early stages of clear cell renal cell carcinoma (ccRCC) are curable, survival outcome for metastatic ccRCC remains poor. The purpose of the current study was to apply a new individualized bioinformatics analysis (IBA) strategy to these transcriptome data in conjunction with Gene Set Enrichment...
ORGANISM(S): Homo sapiens 
2014-08-05 | E-GEOD-54709 | biostudies-arrayexpress
MetabolomicsTime sensitive contribution of the BCAA catabolism to the TCA cycle carbons in HK2, 786-O, OS-RC-2 and RFX-631
Not available
ORGANISM(S): Homo sapiens 
ST002225 | MetabolomicsWorkbench
TranscriptomicsCooperative blockade of CK2 and ATM kinases drives apoptosis in VHL-deficient renal carcinoma cells / RNA-seq (BRB-seq) of treated 786-O spheroids
Multicellular Tumor Spheroids (MCTS) were pre-formed for 3 days with 786-O cell line to better mimic the tumor microenviroenment. These spheroids were treated with either vehicle (DMSO), drugs alone (KU-60019 10 μM; CX-4945 5 μM) or in combination (KU + CX) for 48h before RNA extraction.
ORGANISM(S): Homo sapiens 
2021-02-04 | E-MTAB-9977 | biostudies-arrayexpress
TranscriptomicsBRBseq performed on 786-O cells treated with 2 inhibitors of protein kinase CK2, CX4945 and AB668
786-O cells (150, 000) were treated for 24h with DMSO, 5 µM of CX4945 or AB668. Total RNA was extracted from treated cells using the MirVana PARIS kit (Thermofisher). The 3′ Bulk RNA Barcoding and sequencing (BRB-seq) experiments were performed at the Research Institute for Environmental and Occupat...
ORGANISM(S): Homo sapiens 
2023-05-27 | E-MTAB-12776 | biostudies-arrayexpress
GenomicsGenome-wide mapping of HIF-2 binding in 786-O clear cell renal carcinoma cells
Kidney cancer accounts for more than 100,000 deaths per year world-wide. More than 80% are clear cell tumors (ccRCCs) and the majority are associated with loss of function of the von Hippel Lindau (pVHL) tumor suppressor resulting in upregulation of HIF-{alpha} subunits, and activation of HIF-depend...
ORGANISM(S): Homo sapiens 
2012-02-01 | E-GEOD-34871 | biostudies-arrayexpress
Transcriptomics786-O and 786-VHL in EMCV study
786-0 is a cell line derived from a clear cell renal carcinoma. Previous studies have shown that the 786-O cell line harbors an inactivating mutation in the von-Hippel Lindau (VHL) gene. Mutations in the VHL gene occur in the majority of sporadic clear cell renal cell. To determine how inactivat...
ORGANISM(S): Homo sapiens 
2010-06-23 | E-GEOD-22256 | biostudies-arrayexpress
ProteomicsLC-MSMS of mitochondria of human 786-O cells
Mass spectrum analysis of mitochondria isolated from 786-O cells
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD033099 | Pride
Humna Mitochondria 786-o 
ProteomicsLC-MS of migrasomes and vesicles form human ccRCC 786-O cells
On one hand, we performed label-free quantitative proteomics to analyze migrasome proteins derived from 786-O cells vs ITM2B-knockdown 786-O cells.On the other hands,we isolated ITM2B truncation-containing vesicles and performed mass proteomic analysis to identify proteins that were carried by ITM2B...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD054746 | Pride
Migrasome Vesicle Ccrcc 
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