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TranscriptomicsExpression data from human fibroblasts 6 and 12 hours after 8-oxoguanine treatment
8-oxoguanine is excised from DNA by 8-oxoguanine DNA glycosylase-1 during DNA base excision repair. We used microarrays to gain insight into the potential biological function of the excised, free 8-oxoguanine base. MRC5, human diploid fibroblasts were exposed to 8-oxoguanine and changes in gene expr...
ORGANISM(S): Homo sapiens 
2011-01-27 | E-GEOD-26813 | biostudies-arrayexpress
Proteomics8-Oxoguanine DNA glycosylase 1 conceals guanine oxidation in nucleoprotein-associated RNA of respiratory syncytial virus
Respiratory syncytial virus (RSV), along with other prominent respiratory RNA viruses such as influenza and SARS-CoV-2, significantly contributes to the global incidence of respiratory tract infections. These pathogens induce the production of reactive oxygen species (ROS), which play a crucial role...
ORGANISM(S): Homo sapiens (Human) Human respiratory syncytial virus A 
2024-10-09 | PXD053262 | Pride
Oxidative stress Ogg1 8-oxoguanine Rna oxidation 
TranscriptomicsExpression data from human fibroblasts 6 and 12 hours after 8-oxoguanine treatment
8-oxoguanine is excised from DNA by 8-oxoguanine DNA glycosylase-1 during DNA base excision repair. We used microarrays to gain insight into the potential biological function of the excised, free 8-oxoguanine base.
ORGANISM(S): Homo sapiens 
2011-01-27 | GSE26813 | GEO
GenomicsGenome-wide mapping of oxidative DNA damage via engineering of 8-oxoguanine DNA glycosylase
Genome-wide mapping of oxidative DNA damage via engineering of 8-oxoguanine DNA glycosylase
PRJNA563884 | ENA
OtherGenome-wide mapping of oxidative DNA damage via engineering of 8-oxoguanine DNA glycosylase
7,8-dihydro-8-oxoguanine (OG) is one of the major DNA oxidative damages, which has been concerned by researchers for its potential of mutagenesis and epigenetic regulation. Genome-wide mapping of oxidative DNA damage is of great value for understanding the biological impact of these modifications. H...
ORGANISM(S): Mus musculus 
2019-10-18 | GSE136862 | GEO
UnknownCrystal structures of two archaeal 8-oxoguanine DNA glycosylases provide structural insight into guanine/8-oxoguanine distinction.
Not available
S-EPMC2758660 | biostudies-literature
GenomicsImmunoprecipitation from rat kidney with 8-oxoguanine
8-oxoguanine (8-oxoG) is one of the most common DNA lesions generated by reactive oxygen species. Here we show the genome-wide distribution of 8-oxoG by coupling immunoprecipitation by antibodies specific for the DNA fragments containing 8-oxoG with microarray that covers rat genome. Genome-wide map...
ORGANISM(S): Rattus norvegicus 
2014-01-13 | GSE54007 | GEO
UnknownEpigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1.
Not available
S-EPMC10436556 | biostudies-literature
GenomicsTelomeric 8-Oxoguanine Drives Rapid Premature Senescence in the Absence of Telomere Shortening
Telomeric 8-Oxoguanine Drives Rapid Premature Senescence in the Absence of Telomere Shortening
PRJNA733186 | ENA
UnknownCloning and characterization of a mammalian 8-oxoguanine DNA glycosylase.
Not available
S-EPMC23838 | biostudies-literature
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