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MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
GenomicsTranscriptomic analysis of NF2 deficient AB12 cells
Transcriptomic analysis of NF2 deficient AB12 cells
PRJNA658530 | ENA
GenomicsAcinetobacter baumannii strain:AB12 | isolate:MDR
Acinetobacter baumannii strain:AB12 | isolate:MDR Genome sequencing
PRJNA1350089 | ENA
TranscriptomicsTranscriptomic analysis of NF2 deficient AB12 cells
We developed Ab12 cells with reduced levels of Nf2 by usin shRNA
ORGANISM(S): Homo sapiens 
2021-09-30 | GSE156620 | GEO
ProteomicsImmunopeptidomics of malignant mesothelioma to identify target antigens for T cell Immunotherapy
Immunoaffinity purification was performed on human mesothelioma cell lines NCI-H2452, NCI-H28, MSTO-211H and JL1, on murine mesothelioma cell line AB12, as well as on mesothelioma samples from two patients (including tumor and benign tissues). Thereafter Immunopeptidomics by Mass Spectrometry on a T...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-09-08 | PXD038273 | Pride
Jl1 H28 Msto211h Ab12 Ligandome Malignant pleural mesothelioma Cell lines Immunopeptidome Ligandomics Immunopeptidomics H2452 Cancer 
TranscriptomicsDeep dive to the immune response against murine mesothelioma delineates a roadmap for preclinical investigations to advance anti-mesothelioma immune therapeutics
RNA sequencing data from syngeneic peritoneal tumors induced by the AB12 biphasic murine mesothelioma cell line were generated to determine molecular and immune changes during the kinetics of tumor growth.
ORGANISM(S): Mus musculus 
2022-12-22 | GSE197542 | GEO
UnknownIncreasing dietary selenium elevates reducing capacity and ERK activation associated with accelerated progression of select mesothelioma tumors.
Not available
S-EPMC3969994 | biostudies-literature
UnknownGlycoprotein Receptor CEACAM5-Targeted Intraoperative Molecular Imaging Tracer in Non-Small Cell Lung Cancer.
Not available
S-EPMC9701246 | biostudies-literature
UnknownWing vein abnormality analysis in honeybee (Apis mellifera L. 1758) populations from Iran.
Not available
S-EPMC11335744 | biostudies-literature
GenomicsDeep dive to the immune response against murine mesothelioma delineates a roadmap for preclinical investigations to advance anti-mesothelioma immune therapeutics
Deep dive to the immune response against murine mesothelioma delineates a roadmap for preclinical investigations to advance anti-mesothelioma immune therapeutics
PRJNA810858 | ENA
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