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TranscriptomicsGene expression profiling of ABCB1 positive and ABCB1 negative OCM1A cells
Gene expression profiling of ABCB1 positive and ABCB1 negative OCM1A cells. ABCB1 is an ATP-dependent transporter efflux pump. OCM1A cell line is derived from uveal melanomas. 6 samples (3 ABCB1 positive and 3 ABCB1 negative) from 3 independent ABCB1 shift assays were analysed
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-21425 | biostudies-arrayexpress
ModelsBabaev2025 - CYP2C9 and ABCB1 losartan metabolism model
The model can simultaneously predict the profiles of both losartan and its active metabolite, E-3174, based on a given patient's CYP2C9 and ABCB1 genotypes. The CYP2C9 alleles considered are CYP2C9*1 and CYP2C9*3; the ABCB1 alleles considered are 2677G, 2677T, 3435C, and 3435T. The model includes fi...
2025-09-08 | MODEL2504020001 | BioModels
TranscriptomicsGene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4
The aim of this study is to analyze the change in genome wide expression levels in HAP1 cells upon loss of SMARCB1, SMARCA4 or both these genes together. The SMARCB1 and SMARCA4 genes were the hits from a genome wide screen involving genetrap mutagenesis to find new players that are involved in sen...
ORGANISM(S): Homo sapiens 
2016-08-22 | E-GEOD-75515 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of ABCB1 positive and ABCB1 negative OCM1A cells
Gene expression profiling of ABCB1 positive and ABCB1 negative OCM1A cells. ABCB1 is an ATP-dependent transporter efflux pump. OCM1A cell line is derived from uveal melanomas.
ORGANISM(S): Homo sapiens 
2010-09-01 | GSE21425 | GEO
ProteomicsData in support of Omics investigation of the Intestinal inflammation and Gut Microbiota in ABCB1a Gene Knock-Out Mouse model
Colon cancer (CRC) and chronic inflammatory bowel disease (IBD) are two common gastrointestinal diseases that have a high impact on the quality of life of the affected individuals and their families as well as on the society. The aim of the present study was to contribute to the understanding of the...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD016223 | Pride
Proteomics Abcb1 Ibd Crc 
GenomicsHomo sapiens
Gene expression profiling of ABCB1 positive and ABCB1 negative OCM1A cells
PRJNA126379 | ENA
GenomicsOvercoming ABCB1 mediated multidrug resistance in castration resistant prostate cancer
Overcoming ABCB1 mediated multidrug resistance in castration resistant prostate cancer
PRJNA1129561 | ENA
GenomicsTepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1
Tepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1
PRJNA725471 | ENA
GenomicsPhenotypic consequences of SLC25A40-ABCB1 fusions beyond drug resistance in High Grade Serous Ovarian Cancer
Phenotypic consequences of SLC25A40-ABCB1 fusions beyond drug resistance in High Grade Serous Ovarian Cancer
PRJNA759615 | ENA
TranscriptomicsTepoxalin increases chemotherapy efficacy in drug-resistant breast cancer cells overexpressing the multidrug transporter gene ABCB1
Efficacious cancer chemotherapeutic treatment requires both therapy delivery and retention by malignant cells. Cancer cell overexpression of the multidrug transmembrane transporter gene ABCB1 thwarts therapy retention, leading to a drug-resistant phenotype. We explored the phenotypic impact of ABCB1...
ORGANISM(S): Homo sapiens 
2021-08-04 | GSE173411 | GEO
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