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ProteomicsS-acylproteomic analysis of human prostate cancer LNCaP cells by LB-ABE
Deep S-acylproteomic analysis of LNCaP cells by coupling LB-ABE with label-free quantitative proteomics
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013187 | Pride
Palmitoylation  s-acylation  palmitoyl-proteomics  s-acylproteomics  lncap  lb-abe 
ProteomicsSILAC analysis of proteins enriched from LNCaP cells by ABE
The study was to identify candidate S-acylated proteins from LNCaP cells by coupling SILAC quantification with ABE enrichment of S-acylated proteins and GeLC-MS/MS analysis. Another goal is to determine the ratio of candidate S-acylated proteins versus of co-isolated non-S-acylated proteins.
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD013189 | Pride
Silac  prostate cancer  lncap  abe  palmitoylation  s-acylation  palmitoyl-proteomics 
Proteomicsn-Dodecyl-β-D-maltopyranoside (DDM)-Assisted Resolubilization Enhances S-Palmitoylation Proteomics
This study demonstrates that adding the non-ionic surfactant n-dodecyl-β-D-maltopyranoside (DDM) during protein resolubilization improves the identification of hydrophobic peptides and proteins in bottom-up proteomics. DDM's effectiveness in overcoming the challenge of losing hydrophobic proteins af...
ORGANISM(S): Homo sapiens (Human) 
2025-12-16 | PXD068353 | Pride
Macrophages Protein resolubilization Immunoproteomics N-dodecyl-β-d-maltopyranoside (ddm) Hydrophobic proteome S-palmitoylation 
ProteomicsProteome-wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights into Early Immune Signaling
To understand protein S-palmitoylation's role in macrophage reprogramming, dynamic changes were comprehensively mapped in immortalized mouse macrophages during early LPS stimulation using acyl-biotin exchange (ABE) proteomics enhanced with multi-protease digestion. This approach identified 2613 puta...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-20 | PXD063463 | Pride
Macrophage Acyl-biotin exchange (abe) Palmitoylation Immune signaling S-acylation Post-translational modification Lipopolysaccharide (lps) Multi-protease digestion Proteomics 
ProteomicsPalm oil-rich diet affects murine liver proteome and S-palmitoylome
Palmitic acid (C16:0) is the most abundant saturated fatty acid in animals serving as a substrate in lipid synthesis and β-oxidation, and in the modification of proteins called palmitoylation. The influence of dietary palmitic acid on protein palmitoylation in the context of metabolic processes rema...
ORGANISM(S): Mus musculus (Mouse) 
2021-12-14 | PXD025935 | Pride
S-palmitoylation Neutrophil degranulation Mass spectrometry High-fat diet Palm oil Calfacilitin/tlcd1 
Proteomicsn-Dodecyl-β-D-maltopyranoside (DDM)-Assisted Resolubilization Enhances Hydrophobic Peptide and Protein Identification in Bottom-Up Proteomics
This study demonstrates that adding the non-ionic surfactant n-dodecyl-β-D-maltopyranoside (DDM) during protein resolubilization improves the identification of hydrophobic peptides and proteins in bottom-up proteomics. DDM's effectiveness in overcoming the challenge of losing hydrophobic proteins af...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-16 | PXD064279 | Pride
Macrophages Protein resolubilization Immunoproteomics N-dodecyl-β-d-maltopyranoside (ddm) Hydrophobic proteome S-palmitoylation 
ProteomicsStress-induced changes in the S-palmitoylation and S-nitrosylation of proteins involved in synaptic plasticity
Summary The precise regulation of synaptic integrity is critical for neuronal network connectivity and proper brain function. Essential aspects of the activity and localization of synaptic proteins are regulated by posttranslational modifications. S-palmitoylation is a reversible covalent modificati...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-16 | PXD010822 | Pride
Ptm's interplay Cell signaling Mass spectrometry Postsynaptic density synapse Nitrosylation palmitoylation 
ProteomicsA rapid and convenient sample treatment method based on the dissolvable polyacrylamide gel for S-acylation proteomics
S-acylation, dissolvable gel, sample treatment, proteomics
ORGANISM(S): Mus Musculus 
2024-06-04 | PXD052808 |
ProteomicsSynaptic protein S-palmitoylation as a novel mechanism underlying sex-dependent differences in neuronal plasticity
Although sex differences in the brain are prevalent, the knowledge about mechanisms underlying sex-related effects on normal and pathological brain functioning is rather poor. It is known that female and male brains differ in size and connectivity. Moreover, those differences are related to neuronal...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-23 | PXD025286 | Pride
Sex-dependent Dhhc7 Palmitoylation 
UnknownLow-Background Acyl-Biotinyl Exchange Largely Eliminates the Coisolation of Non-S-Acylated Proteins and Enables Deep S-Acylproteomic Analysis.
Not available
S-EPMC7451198 | biostudies-literature
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