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MetabolomicsSex-dependent metabolic remodeling of kidneys revealed by arteriovenous metabolomics

Sex is a fundamental biological variable important in biomedical research, drug development, clinical trials, and prevention approaches. Among many organs, kidneys are known to exhibit remarkable structural, histological, and pathological differences between sexes. However, whether and how kidney...

2026-03-04 | MTBLS13977 | MetaboLights
MetabolomicsSex-dependent effects of FGF21 on hepatic metabolism
Not available
ORGANISM(S): Mus musculus 
ST002249 | MetabolomicsWorkbench
MetabolomicsTitanium dioxide in food induces sex- and microbiota-dependent metabolic disorders, and worsens high-fat diet outcomes
Ultra-processed food consumption has been linked to the rising global burden of metabolic diseases, but the specific contribution of additives commonly used in these products remains unclear. Given the bactericidal properties of the food-grade (fg) additive titanium dioxide (TiO2) and the key role o...
2026-05-19 | MTBLS14529 | MetaboLights
TranscriptomicsSex-dependent and STAT5b-dependent Liver Gene Expression
A series of dual-channel gene expression profiles obtained using Rosetta/Merck Mouse TOE 75k microarrays was used to examine the sex-dependent and STAT5b-dependent differences in gene expression in adult mouse liver. This series is comprised of 4 pools of 3 randomly chosen independent wildtype male ...
ORGANISM(S): Mus musculus 
2010-07-01 | E-GEOD-5072 | biostudies-arrayexpress
TranscriptomicsSex-dependent gene regulatory networks of the heart rhythm
Expression level, control and intercoordination of 66 selected heart rhythm determinant (HRD) genes were compared in atria and ventricles of 4 male and 4 female adult mice. We found that genes encoding various adrenergic receptors, ankyrins, ion channels and transporters, connexins and other compone...
ORGANISM(S): Mus musculus 
2009-08-12 | E-GEOD-17324 | biostudies-arrayexpress
TranscriptomicsEvolution of sex-dependent gene expression in three recently diverged species of Drosophila
To identify the transcriptome divergence and sex roles underlying it in recently diverged Drosophia pseudoobscura group, we compare the global gene expression of 7-day-old whole body adults of pure species. 7-day-old virgin flies were assayed by species and sex. At least three isofemale inbred line...
ORGANISM(S): Drosophila persimilis 
2010-05-16 | E-GEOD-17192 | biostudies-arrayexpress
ProteomicsSynaptic protein S-palmitoylation as a novel mechanism underlying sex-dependent differences in neuronal plasticity
Although sex differences in the brain are prevalent, the knowledge about mechanisms underlying sex-related effects on normal and pathological brain functioning is rather poor. It is known that female and male brains differ in size and connectivity. Moreover, those differences are related to neuronal...
ORGANISM(S): Mus musculus (Mouse) 
2021-06-23 | PXD025286 | Pride
Sex-dependent Dhhc7 Palmitoylation 
ProteomicsMultilayered Omics Revealsl Sex- and Depot-Dependent Adipose Progenitor Cell Heterogeneity
White adipose tissue (WAT) harbors functionally diverse subpopulations of adipose progenitor cells that differentially impact tissue plasticity in a sex- and depot-dependent manner. To date, the molecular basis of this cellular heterogeneity has not been fully defined. Here, we describe a multilayer...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD023829 | Pride
Multilayered omics Adipogenesis Inflammation Preadipocytes Ppar. Adipocyte precursor cells Cellular heterogeneity 
TranscriptomicsExpression of the placental transcriptome in fetal growth restriction in the Baboon is Dependent on Fetal Sex
Fetal growth restriction (FGR) develops when fetal nutrient availability is compromised and increases the risk for perinatal complications and predisposes for offspring obesity, diabetes and cardiovascular disease later in life. Emerging evidence implicates changes in placental function in altered f...
ORGANISM(S): Papio hamadryas 
2013-12-06 | E-GEOD-40878 | biostudies-arrayexpress
GenomicsMultilayer-omics Reveal Sex- and Depot-Dependent Adipose Progenitor Cell Heterogeneity
Multilayer-omics Reveal Sex- and Depot-Dependent Adipose Progenitor Cell Heterogeneity
PRJNA695213 | ENA
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