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Two month-old male Wistar rats received either resveratrol (10 mg/kg) plus N-acetylcysteine (400 mg/kg) or vehicle during 5 consecutive days. The second day of treatment, a concentrated solution of kanamycin and furosemide was placed on the round window of the right ears of rats receiving treatment ...
ORGANISM(S): Rattus norvegicus 
We previously showed that exposure of rats to environmental cigarette smoke (ECS) causes extensive downregulation of microRNA expression in the lung, resulting in overexpression of multiple genes and proteins. In the present study, we evaluated by microarray the expression of 484 microRNAs in the l...
ORGANISM(S): Rattus norvegicus 
RNA-seq analysis of methylglyoxal- and N-acetylcysteine-treated SH-SY5Y cells
Transcriptomic response of Pseudomonas aeruginosa Z154 planktonic cultures to N-acetylcysteine exposure.
We tested the effects of the antioxidant NAC (N-Acetyl-Cysteine) on gene expression in Nkx3.1-deficient mouse prostate. Mice that were homozygous null for Nkx3.1 were given NAC or plain water ad libidum for 13 weeks after weaning. Prostates were collected, RNA was harvested and reverse transcribed, ...
ORGANISM(S): Mus musculus 
In this study, we used the adult zebrafish model of ACR acute neurotoxicity for determining the suitability of NAC to protect the brain against ACR toxicity. First, the potential protective effects of NAC on the ACR neurotoxicity were evaluated at the behavioral and molecular (transcriptome and prot...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2020-05-26 | PXD014228 | Pride
This SuperSeries is composed of the following subset Series:; GSE11550: Hs 294T Cells Treated with Elesclomol Alone or in Combination with Paclitaxel Compared to DMSO Treated; GSE11551: Hs 294T Cells Treated with Elesclomol Alone or in Combination with NAC Compared to DMSO Treated Experiment Overall...
ORGANISM(S): Homo sapiens 
N-acetylcysteine (NAC) is a mucolytic agent commonly administered together with antibiotics for the treatment of lower respiratory tract infections, which has been demonstrated to exert also an antimicrobial and antibiofilm activity against relevant respiratory pathogens. We analysed the transcripto...
ORGANISM(S): Pseudomonas aeruginosa 
2022-05-30 | GSE190946 | GEO
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