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Background: Dyslipidemia is a significant contributor to many eye diseases and the lipid processing pathways are not well understood. Peroxisomes oxidize very long-chain, monocarboxylic and dicarboxylic fatty acids. Genetic mutations in peroxisomal proteins may lead to severe neural retinal degenera...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-15 | PXD055240 | Pride
Gene expression in liver from WT/ACOX1 liver specific knockout mice
Effect of knockdown ACOX1 on gene expression in HK-2 cells
This RNA-seq dataset was generated to investigate the transcriptional changes induced by ACOX1 overexpression in synovial fibroblasts. Synovial fibroblasts were divided into two experimental groups: a control group and an ACOX1-overexpression group. Each group consisted of six biological replicates....
ORGANISM(S): Mus musculus 
2026-10-05 | GSE349121 | GEO
To investigate the role of ACOX1, we knocked down ACOX1 by shRNA in HK-2 cell lines and detected differential genes. We then performed gene expression profiling analysis using data obtained from RNA-seq of 2 different cells.
ORGANISM(S): Homo sapiens 
2024-02-02 | GSE205057 | GEO
The target of this project is to investigate the effect of ACOX1 knockout in liver Gene expression profiling analysis were performed using data obtained from RNA-seq of two genotypes mice liver
ORGANISM(S): Mus musculus 
2024-03-20 | GSE227896 | GEO
Genomics
HK-2 ACOX1-Hypoxia RNA-seq
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