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HPLC-MS/MS analysis of actin peptide with methionine methylation
ORGANISM(S): Homo sapiens (Human) 
2020-06-24 | PXD019203 | Pride
To facilitate biochemical studies of human cytoplasmic actins, Saccharomyces cerevisiaestrains were developed that express either human β-actin or γ-actin as their sole actin. Actins purified from these strains have biochemical properties similar to mammalian skeletal muscle α-actin, but display di...
ORGANISM(S): Oryctolagus sp. 'Rabbit_OD' Homo sapiens (Human) Saccharomyces cerevisiae (Baker's yeast) 
2023-04-24 | PXD040174 | Pride
The aim of this work is to characterize the Plasmodium berghei actin II during mosquito stages with special focus on post-translational modification of histidine.
ORGANISM(S): Plasmodium berghei 
2023-02-16 | PXD033378 | Pride
The global impact of DNA methylation on alternative splicing is largely unknown. Using a genome-wide approach in wild-type and methylation-deficient embryonic stem cells, we found that DNA methylation can act both as an enhancer and as a silencer of splicing, and affects the splicing of more than 20...
ORGANISM(S): Mus musculus 
Eukaryotic chromatin is separated into functional domains differentiated by posttranslational histone modifications, histone variants, and DNA methylation. Methylation is associated with repression of transcriptional initiation in plants and animals, and is frequently found in transposable elements...
ORGANISM(S): Arabidopsis thaliana 
Pilocytic astrocytomas (PA) are the most common brain tumor in pediatric patients and can cause significant morbidity, including chronic neurological deficiencies. They are characterized by activating alterations in the mitogen-activated protein kinase (MAPK) pathway, but little else is known about ...
ORGANISM(S): Homo sapiens 
Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patterns which could lead to altered gene expression Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 ...
ORGANISM(S): Homo sapiens 
Apicomplexan parasites rely on actin-based motility for host cell invasion and for their dissemination. Although previous studies implicate formin 1 (FRM1) in governing this process in Toxoplasma, the mechanisms that position it at the cell apex and regulate its activity during the transition from i...
ORGANISM(S): Toxoplasma gondii ME49 
2025-11-04 | PXD068228 | Pride
Fifteen DNA methylation array experiments were performed on five human chromosome specific array platforms (NimbleGen: HG18_CHR13_FT, HG18_CHR18_FT, HG18_CHR21_FT, HG18_CHRX_FT, HG18_CHRY_FT), comparing: (1) one female whole blood immunoprecipitated DNA fragments to their input DNA, (2) one 1st tri...
ORGANISM(S): Homo sapiens 
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