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Adenomyosis, defined as ectopic endometrial tissue within the myometrium, can often be misdiagnosed as multiple uterine leiomyomata or endometrial thickening. We therefore performed a combined mRNA and long noncoding (lnc)RNA microarray and bioinformatic analysis of eutopic and ectopic endometri...
ORGANISM(S): Homo sapiens 

This analysis established comprehensive metabolomic profiles of adenomyosis patients and revealed widespread alterations in the metabolome within normal and fibrotic myometrium. Integrated analysis shown significant associations between metabolomic data and fibrosis . This study is the first to d...

2025-05-12 | MTBLS11965 | MetaboLights
Abstract: Objective: Adenomyosis is a clinical disorder defined by the presence of endometrial glands and stroma within the myometrium, the pathogenesis of which is poorly understood. We postulate that dysregulation of genes and pathways in eutopic endometrium may predispose to ectopic implantat...
ORGANISM(S): Homo sapiens 
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) was utilized to analyze adenomyotic and normal myometrial tissues from ten AM patients who underwent hysterectomy with myometrial fibrosis confirmed by Masson staining. This analysis established comprehensive proteomic profiles of adenomyosi...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD058989 | Pride
Arraystar Human m6A-mRNA&lncRNA Epitranscriptomic microarray analysis in adenomyosis and non-adenomyosis patients
Adenomyosis is a common benign gynecological condition causing abnormal uterine bleeding, dysmenorrhea, chronic pelvic pain, as well as infertility . Histologically, adenomyosis is defined by the presence of ectopic endometrial glands and stroma surrounded by hypertrophic and hyperplastic myometrium...
ORGANISM(S): Homo sapiens (Human) 
2025-01-14 | PXD055131 | Pride
Transcriptome analysis of adenomyosis eutopic endometrium reveals molecular mechanisms involved in adenomyosis-related implantation failure and pregnancy disorders
Adenomyosis mostly occurs in the females with reproductive age, and the pathogenesis is not clear. If we want to improve the diagnosis and treatment of adenomyosis, we must fully understand the specific molecular mechanism of adenomyosis. The Arraystar Human m6a-mRNA&lncRNA Epitranscriptomic microar...
ORGANISM(S): Homo sapiens 
2022-10-06 | GSE214850 | GEO
Bromocriptine inhibits proliferation in eutopic endometrium from women with adenomyosis
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