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ProteomicsSARS-CoV2 manipulates multiple NK ligands and inhibits NK activation, but this can be overcome by ADNKA, which is strongly activated by non-Spike targeting antibodies
SARS-CoV2 is recognised the antagonise the interferon response, and functioning interferon responses are critical in determining the severity of disease. However, whether the virus antagonises cellular immunity has not been determined. We used quantitative plasma membrane proteomics in lung epitheli...
ORGANISM(S): Homo sapiens (Human) 
2022-05-26 | PXD025000 | Pride
Sars-cov2 Nk ligands Adnka 
UnknownDifferential contribution of education through KIR2DL1, KIR2DL3, and KIR3DL1 to antibody-dependent (AD) NK cell activation and ADCC.
Not available
S-EPMC6916277 | biostudies-literature
UnknownA protein-based pneumococcal vaccine elicits broad immunity associated with multifunctional antibody responses in humans.
Not available
S-EPMC12867161 | biostudies-literature
UnknownDifference in respiratory syncytial virus-specific Fc-mediated antibody effector functions between children and adults.
Not available
S-EPMC10711356 | biostudies-literature
UnknownSARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies.
Not available
S-EPMC9239683 | biostudies-literature
UnknownPrimary SARS-CoV-2 infection in children and adults results in similar Fc-mediated antibody effector function patterns.
Not available
S-EPMC11273100 | biostudies-literature
ProteomicsDecreased Fc fucosylation aligns with enhanced RSV-specific antibody functionality in adults compared to young children
Respiratory syncytial virus (RSV) is a major cause of severe respiratory tract infections in infants and older adults. While vaccines have recently been approved for older adults and pregnant women, vaccine development for infants remains challenging due to the risk of vaccine-enhanced disease. Unde...
ORGANISM(S): Homo sapiens (Human) 
2025-11-05 | PXD069590 | Pride
Fc-glycosylation Antibody maturation Respiratory virus Fc-functionality 
UnknownNeurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses.
Not available
S-EPMC11004923 | biostudies-literature
UnknownSerum Fc-Mediated Monocyte Phagocytosis Activity Is Stable for Several Months after SARS-CoV-2 Asymptomatic and Mildly Symptomatic Infection.
Not available
S-EPMC9769986 | biostudies-literature
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