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GenomicsMacrophage response to extracellular ADP stimulation
Macrophage response to extracellular ADP stimulation
PRJNA644410 | ENA
MetabolomicsExamination of labeled glucose utilization in central carbon metabolism in HeLa cells post WNT stimulation
Not available
ORGANISM(S): Homo sapiens 
ST001320 | MetabolomicsWorkbench
ProteomicsQuantitative Phosphorylation analysis in human platelets after ADP stimulation
Human platelets were treated with 20 µM of ADP for 10, 30 and 60 s in triplicate. In a second experiment blood donations of three donors were split again in four fractions and one was treated with 20 µM of ADP and the second and third with 20 µM of ADP for 30 s and subsequently with 2 nM of Ilopros...
ORGANISM(S): Homo sapiens (Human) 
2017-03-14 | PXD001189 | Pride
Phosphorylation Platelets Adp stimulation 
TranscriptomicsMacrophage response to extracellular ADP stimulation
The gene expression analysis of bone marrow-derived macrophages (BMDM) treated with 100uM ADP was employed. Extracellular ADP is a danger signal that induces immune responses. Results provide insight into macrophage functions altered in ADP stimulation.
ORGANISM(S): Mus musculus 
2020-07-07 | GSE153888 | GEO
TranscriptomicsMouse Soleus Muscle Chronic Electrical Stimulation Study
Stimulation of the mouse hindlimb via the sciatic nerve was used to induce contractions for 4 hours to investigate acute muscle gene activation in a model of muscle phenotype conversion. Initial force production (1.6 + 0.1 g/g body weight) declined 45% within 10 min and was maintained for the remain...
ORGANISM(S): Mus musculus 
2010-06-01 | E-GEOD-14391 | biostudies-arrayexpress
GenomicsTranscriptomic analysis of ALPK1-dependent responses in BMDMs from WT and ALPK1 knockout C57BL/6 mice upon ADP-Hep stimulation
Transcriptomic analysis of ALPK1-dependent responses in BMDMs from WT and ALPK1 knockout C57BL/6 mice upon ADP-Hep stimulation
PRJNA1330749 | ENA
ProteomicsProtein ADP-ribosylation, phosphorylation, and interactome dynamics in macrophage activation.
The innate immune response relies on efficient, robust and fast protein signaling networks to relay information related to pathogen or viral detection. This communication is mediated primarily through protein-protein interactions and post-translational modifications (PTMs), events which are best cha...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2020-06-17 | PXD016469 | Pride
Lps Macrophage Imac Ask2 Phosphorylation Parp Adp-ribosylation Size exclusion chromatography Parp9 Sec Interactome 
TranscriptomicsTranscription profiling of human Parp-1 deficient and wild type T cells following CD3 and CD3/CD28 activation
Primary T cells were isolated from spleen of Parp-1-/- and wild-type mice by magnetic depletion of non-T cells using a MACS Pan-T Cell isolation kit, according to the manufacturer´s instruction (Mintenyi Biotec, Bergisch Gladbach, Germany). Purity was assessed by flow cytometry analysis using antibo...
ORGANISM(S): Mus musculus 
2008-08-04 | E-MEXP-1237 | biostudies-arrayexpress
ProteomicsPARylation of UBC13 and PDI proteins
NH2OH was used to remove PAR from the PARylated proteins. This treatment left on the PARylated residues a hydroxamic acid derivative, which has a signature mass increase of +15.0109 Da and could be distinguished by mass spectrometry.
ORGANISM(S): Arabidopsis Thaliana (ncbitaxon:3702) 
2021-07-23 | MSV000087876 | MassIVE
TranscriptomicsTranscriptomic analysis of ALPK1-dependent responses in BMDMs from WT and ALPK1 knockout C57BL/6 mice upon ADP-Hep stimulation
The ALPK1 pathway is a cytosolic sensor for the bacterial metabolite ADP-heptose (ADP-Hep), triggering innate immune signalling. To investigate ALPK1-dependent transcriptional responses, bone marrow-derived macrophages (BMDMs) were generated from wild-type (WT) and Alpk1 knockout C57BL/6 mice using ...
ORGANISM(S): Mus musculus 
2025-10-10 | GSE308482 | GEO
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